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The following results are related to COVID-19. Are you interested to view more results? Visit OpenAIRE - Explore.
5,684 Research products, page 1 of 569

  • COVID-19
  • Other research products
  • 2012-2021
  • Open Access
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  • Open Access English
    Authors: 
    Mamelund, Svenn-Erik; Dimka, Jessica;
    Publisher: Routledge

    Despite common perceptions to the contrary, pandemic diseases do not affect populations indiscriminately. In this paper, we review literature produced by demographers, historians, epidemiologists, and other researchers on disparities during the 1918–20 influenza pandemic and the Covid-19 pandemic. Evidence from these studies demonstrates that lower socio-economic status and minority/stigmatized race or ethnicity are associated with higher morbidity and mortality. However, such research often lacks theoretical frameworks or appropriate data to explain the mechanisms underlying these disparities fully. We suggest using a framework that considers proximal and distal factors contributing to differential exposure, susceptibility, and consequences as one way to move this research forward. Further, current pandemic preparedness plans emphasize medically defined risk groups and epidemiological approaches. Therefore, we conclude by arguing in favour of a transdisciplinary paradigm that recognizes socially defined risk groups, includes input from the social sciences and humanities and other diverse perspectives, and contributes to the reduction of health disparities before a pandemic hits.

  • Open Access English
    Authors: 
    Banco de España;
    Publisher: Banco de España
    Country: Spain
  • Open Access English
    Authors: 
    Kinsella, Cormac M.; Santos, Pauline Dianne; Postigo-Hidalgo, Ignacio; Folgueiras-González, Alba; Passchier, Tim Casper; Szillat, Kevin P.; Akello, Joyce Odeke; Álvarez-Rodríguez, Beatriz; Martí-Carreras, Joan;

    The first cluster of patients suffering from coronavirus disease 2019 (COVID-19) was identified on December 21, 2019, and as of July 29, 2020, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections have been linked with 664,333 deaths and number at least 16,932,996 worldwide. Unprecedented in global societal impact, the COVID-19 pandemic has tested local, national, and international preparedness for viral outbreaks to the limits. Just as it will be vital to identify missed opportunities and improve contingency planning for future outbreaks, we must also highlight key successes and build on them. Concomitant to the emergence of a novel viral disease, there is a 'research and development gap' that poses a threat to the overall pace and quality of outbreak response during its most crucial early phase. Here, we outline key components of an adequate research response to novel viral outbreaks using the example of SARS-CoV-2. We highlight the exceptional recent progress made in fundamental science, resulting in the fastest scientific response to a major infectious disease outbreak or pandemic. We underline the vital role of the international research community, from the implementation of diagnostics and contact tracing procedures to the collective search for vaccines and antiviral therapies, sustained by unique information sharing efforts.

  • Open Access Portuguese
    Authors: 
    Carneiro, António Vaz; Neto, Susana;
    Publisher: ISBE
    Country: Portugal

    O objectivo da Newsletter do Instituto de Saúde Baseado na Evidência (ISBE) é a disponibilização de informação sobre áreas relevantes para a prática clínica, baseada na melhor evidência científica. São localizados estudos relevantes e de alta qualidade, criticamente avaliados pela sua validade, importância dos resultados e aplicabilidade prática e resumidos numa óptica de suporte à decisão clínica. É dada prioridade aos estudos de causalidade – revisões sistemáticas, ensaios clínicos, estudos de coorte prospectivos/retrospectivos, estudos seccionais cruzados e caso‐controlo – incluindo‐se ainda, quando justificado, estudos qualitativos considerados de elevada qualidade metodológica e importância clínica.

  • Other research product . Other ORP type . 2021
    Open Access English
    Authors: 
    Kooman, Jeroen P.; van der Sande, Frank M.;

    The COVID-19 pandemic has greatly affected nephrology. Firstly, dialysis patients appear to be at increased risk for infection due to viral transmission next to an enhanced risk for mortality as compared to the general population, even in the face of an often apparently mild clinical presentation. Derangements in the innate and adaptive immune systems may be responsible for a reduced antiviral response, whereas chronic activation of the innate immune system and endothelial dysfunction provide a background for a more severe course. The presence of severe comorbidity, older age, and a reduction of organ reserve may lead to a rapid deterioration of the clinical situation of the patients in case of severe infection. Secondly, patients with COVID-19 are at increased risk of acute kidney injury (AKI), which is related to the severity of the clinical disease. The presence of AKI, and especially the need for renal replacement therapy (RRT), is associated with an increased risk of mortality. AKI in COVID-19 has a multifactorial origin, in which direct viral invasion of kidney cells, activation of the renin-angiotensin aldosterone system, a hyperinflammatory response, hypercoagulability, and nonspecific factors such as hypotension and hypoxemia may be involved. Apart from logistic challenges and the need for strict hygiene within units, treatment of patients with ESRD and COVID-19 is not different from that of the general population. Extracorporeal treatment of patients with AKI with RRT can be complicated by frequent filter clotting due to the hypercoagulable state, for which regional citrate coagulation provides a reasonable solution. Also, acute peritoneal dialysis may be a reasonable option in these patients. Whether adjuncts to extracorporeal therapies, such as hemoadsorption, provide additional benefits in the case of severely ill COVID-19 patients needs to be addressed in controlled studies.

  • Open Access
    Authors: 
    Direcció de Serveis de Comunicació Digital; Gerència de Recursos; Goroka (Firma); Guerrero, Laura;
    Publisher: Ajuntament de Barcelona
    Country: Spain

    El Departament de Salut i l’Ajuntament de Barcelona van posar en marxa els cribratges massius al Raval Nord de la ciutat. L’objectiu de l’actuació era detectar el màxim de casos asimptomàtics possibles, tallar cadenes de transmissió, aïllar contactes i limitar l’expansió del virus de la Covid-19. L’equip de veïnatge del Districte de Ciutat Vella va realitzar una campanya de difusió amb les comunitats culturals d’origen divers. La consellera de Salut, Alba Vergés i l’alcaldessa de Barcelona, Ada Colau, van destacar la importància de la realització de PCR’s. Imatges del 15 de setembre de 2020.

  • Other research product . Other ORP type . 2021
    Open Access Catalan; Valencian
    Authors: 
    Sindicatura de Greuges de Barcelona;
    Country: Spain

    Nota de premsa elaborada en el context de desconfinament davant l’emergència provocada per la COVID-19. Balanç de l'any 2020 de la Sindicatura de Greuges. Recull de totes les queixes rebudes i actuacions realitzades per la Sindica. Press release prepared in the context of deconfinement to the emergency caused by COVID-19. Nota de prensa elaborada en el contexto de desconfinamiento ante la emergencia provocada por la COVID-19.

  • Open Access Catalan; Valencian
    Authors: 
    Alcaldia;
    Country: Spain

    Aprovat per Decret de l'Alcaldia de 03-05-2020 Aquest decret forma part de les mesures organitzatives establertes en el context de confinament davant l’emergència provocada per la COVID-19. This decree is part of the organizational measures established in the context of confinement to the emergency caused by COVID-19. Este decreto forma parte de las medidas organizativas establecidas en el contexto de confinamiento ante la emergencia provocada por la COVID-19.

  • Open Access Spanish; Castilian
    Authors: 
    Instituto de Salud Carlos III;
    Country: Spain

    Noticia publicada en la web del ISCIII el 30/07/2020. Incluye vídeo de Isabel Cuesta. La bioinformática es una de las disciplinas científicas que más relevancia están teniendo en la investigación del coronavirus SARS-Cov-2 y en el estudio de la pandemia de COVID-19, dada su capacidad para facilitar el análisis del creciente número de datos que las tecnologías biomédicas generan. El ISCIII dispone de una Unidad de Bioinformática (BU-ISCIII) desde el año 2012, dirigida por la investigadora Isabel Cuesta, cuyos servicios están jugando un papel clave en la implicación del Instituto en la investigación y manejo de la pandemia. Sí