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The following results are related to COVID-19. Are you interested to view more results? Visit OpenAIRE - Explore.
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275 research outcomes, page 1 of 28
  • publication . Article . 2020
    Open Access English
    Authors:
    Amin Hosseini; Richa Pandey; Enas Osman; Amanda Victorious; Feng Li; Tohid F. Didar; Leyla Soleymani;
    Persistent Identifiers
    Publisher: American Chemical Society (ACS)
    Project: NSERC

    The disease caused by SARS-CoV-2, coronavirus disease 2019 (COVID-19), has led to a global pandemic with tremendous mortality, morbidity, and economic loss. The current lack of effective vaccines and treatments places tremendous value on widespread screening, early dete...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Conor McDermott; Maciej Łącki; Ben Sainsbury; Henry Jessica; Mihail Filippov; Carlos Rossa;
    Persistent Identifiers
    Publisher: Frontiers Media S.A.
    Project: NSERC

    The sustained increase in new cases of COVID-19 across the world and potential for subsequent outbreaks call for new tools to assist health professionals with early diagnosis and patient monitoring. Growing evidence around the world is showing that lung ultrasound exami...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Xuhua Xia;
    Persistent Identifiers
    Publisher: MDPI AG
    Project: NSERC

    The spike protein in SARS-CoV-2 (SARS-2-S) interacts with the human ACE2 receptor to gain entry into a cell to initiate infection. Both Pfizer/BioNTech’s BNT162b2 and Moderna’s mRNA-1273 vaccine candidates are based on stabilized mRNA encoding prefusion SARS-2-S that ca...

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  • publication . Preprint . Article . 2021
    Open Access English
    Authors:
    Bailey E. McGuire; Julia E Mela; Vanessa C Thompson; Logan R Cucsksey; Claire E Stevens; Ralph L McWhinnie; Dirk F. H. Winkler; Steven L. Pelech; Francis E. Nano;
    Publisher: BMC
    Project: NSERC

    AbstractWe have developed a method for the inexpensive, high-level expression of antigenic protein fragments of SARS-CoV-2 proteins in Escherichia coli. Our approach uses the thermophilic family 9 carbohydrate-binding module (CBM9) as an N-terminal carrier protein and a...

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  • publication . Article . 2019
    Open Access English
    Authors:
    Subudhi, Sonu; Rapin, Noreen; Misra, Vikram;
    Persistent Identifiers
    Publisher: MDPI AG
    Project: NSERC

    Bats harbor a myriad of viruses and some of these viruses may have spilled over to other species including humans. Spillover events are rare and several factors must align to create the “perfect storm„ that would ultimately lead to a spillover. One of these ...

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  • publication . Article . 2019
    Open Access English
    Authors:
    Li, Michael; Bolker, Benjamin M.; Dushoff, Jonathan; Ma, Junling; Earn, David J.D.;
    Persistent Identifiers
    Publisher: BioMed Central
    Project: NSERC

    Background Mathematical and statistical models are used to project the future time course of infectious disease epidemics and the expected future burden on health care systems and economies. Influenza is a particularly important disease in this context because it causes...

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  • publication . Preprint . 2020
    Open Access English
    Authors:
    Dae-Kyum Kim; Jennifer J. Knapp; Kuang D; Aditya Chawla; Patricia Cassonnet; Lee H; Dayag Sheykhkarimli; Payman Samavarchi-Tehrani; Hala Abdouni; Ashyad Rayhan; ...
    Publisher: Preprints
    Project: NSERC , EC | PREPARE (602525), CIHR

    The world is facing a major health crisis, the global pandemic of COVID-19 caused by the SARS-CoV-2 coronavirus, for which no approved antiviral agents or vaccines are currently available. Here we describe a collection of codon-optimized coding sequences for SARS-CoV-2 ...

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  • publication . Article . Preprint . 2020
    Open Access English
    Authors:
    T. R. Hurd;
    Persistent Identifiers
    Country: Canada
    Project: NSERC

    Motivated by the need for novel robust approaches to modelling the Covid-19 epidemic, this paper treats a population of $N$ individuals as an inhomogeneous random social network (IRSN). The nodes of the network represent different types of individuals and the edges repr...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Madalina E. Carter-Timofte; Rozanne Arulanandam; Naziia Kurmasheva; Kathy Fu; Geneviève Laroche; Zaid Taha; Demi van der Horst; Lena Cassin; Renée M. van der Sluis; Enrico Palermo; ...
    Persistent Identifiers
    Publisher: American Chemical Society
    Project: EC | ENVISION (786602), EC | AIAS-COFUND II (754513), CIHR , NSERC

    The antimicrobial medication malarone (atovaquone/proguanil) is used as a fixed-dose combination for treating children and adults with uncomplicated malaria or as chemoprophylaxis for preventing malaria in travelers. It is an inexpensive, efficacious, and safe drug freq...

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  • publication . Preprint . 2020
    Open Access English
    Authors:
    Zhang, Edwin; Gupta, Nikhil; Nogueira, Rodrigo; Cho, Kyunghyun; Lin, Jimmy;
    Project: NSERC

    We present the Neural Covidex, a search engine that exploits the latest neural ranking architectures to provide information access to the COVID-19 Open Research Dataset curated by the Allen Institute for AI. This web application exists as part of a suite of tools that w...

275 research outcomes, page 1 of 28