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141 research outcomes, page 1 of 15
  • publication . Article . 2013
    Open Access English
    Authors:
    Charlotte Lombardi; Maya Ayach; Lionel Beaurepaire; Mélanie Chenon; Jessica Andreani; Raphael Guerois; Isabelle Jupin; Stéphane Bressanelli;
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: ANR | PHOSPHO-POL (ANR-06-BLAN-0062)

    Author Summary Positive-stranded RNA viruses are ultimate parasites. In order to replicate their genome, they first need to invade a host cell and, with usually very limited viral genetic material, subvert the host's molecular machinery. Turnip yellow mosaic virus (TYMV...

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  • publication . Article . Other literature type . 2018
    Open Access
    Authors:
    Mathieu Bourgarel; Davies M. Pfukenyi; Vanina Boué; Loïc Talignani; Ngoni Chiweshe; Fodé Diop; Alexandre Caron; Gift Matope; Dorothée Missé; Florian Liegeois;
    Persistent Identifiers
    Publisher: Elsevier BV
    Project: ANR | TIMTAMDEN (ANR-14-CE14-0029)

    Highlights • Coronavirus and Paramyxovirus circulate in Hipposideros bat species in Zimbabwe. • Importance of widening viral screening in under-investigated countries • Sentinel surveillance in sites with high zoonotic transmission potential

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  • publication . Preprint . Article . 2021
    Restricted English
    Authors:
    Baunez, Christelle; Degoulet, Mickaël; Luchini, Stéphane; Pintus, Patrick A.; Teschl, Miriam;
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: ANR | AMSE (EUR) (ANR-17-EURE-0020)

    Even though much has been learned about the new pathogen SARS-CoV-2 since the beginning of the COVID-19 pandemic, a lot of uncertainty remains. In this paper we argue that what is important to know under uncertainty is whether harm accelerates and whether health policie...

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  • publication . Other literature type . Article . 2020
    Open Access
    Authors:
    Frédéric Lemoine; Luc Blassel; Jakub Voznica; Olivier Gascuel;
    Publisher: Cold Spring Harbor Laboratory
    Project: ANR | PRAIRIE (ANR-19-P3IA-0001)

    <jats:title>Abstract</jats:title><jats:sec><jats:title>Motivation</jats:title><jats:p>The first cases of the COVID-19 pandemic emerged in December 2019. Until the end of February 2020, the number of available genomes was below 1,000, and their multiple alignment was eas...

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  • publication . Article . Other literature type . 2018
    Open Access English
    Authors:
    Cyrille Mathieu; Matteo Porotto; Tiago N. Figueira; Branka Horvat; Anne Moscona;
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: ANR | Avenir L.S.E. (ANR-11-IDEX-0007), NIH | Design of CNS-targeted pe... (5R33AI101333-04), NIH | Engineering protease-resi... (5R01AI114736-04), ANR | ECOFECT (ANR-11-LABX-0048), NIH | MOLECULAR BASIS FOR PARAI... (5R29AI031971-03)

    International audience; Background. The emerging zoonotic paramyxovirus Nipah virus (NiV) causes severe respiratory and neurological disease inhumans, with high fatality rates. Nipah virus can be transmitted via person-to-person contact, posing a high risk for epidemic ...

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  • publication . Preprint . Other literature type . 2020
    Open Access English
    Authors:
    Claude Pasquier; Alain Robichon;
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: ANR | SIGNALIFE (ANR-11-LABX-0028)

    The role of the RNAi/Dicer/Ago system to degrade RNA viruses has been elusive in mammals, which prompted authors to think that interferon (IFN) synthesis is essential in this clade relegating the RNAi defense strategy against viral infection as accessory function. We ex...

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  • publication . Article . 2015
    Open Access English
    Authors:
    Clément Cocita; Rachel Guiton; Gilles Bessou; Lionel Chasson; Marilyn Boyron; Karine Crozat; Marc Dalod;
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: ANR | Amidex (ANR-11-IDEX-0001), ANR | PSL (ANR-10-IDEX-0001)

    In mice, plasmacytoid dendritic cells (pDC) and natural killer (NK) cells both contribute to resistance to systemic infections with herpes viruses including mouse Cytomegalovirus (MCMV). pDCs are the major source of type I IFN (IFN-I) during MCMV infection. This respons...

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  • publication . Article . 2019
    Open Access
    Authors:
    Sibylle Bernard-Stoecklin; Birgit Nikolay; Abdullah M. Assiri; Abdul Aziz Bin Saeed; Peter Ben Embarek; Hassan El Bushra; Moran Ki; Mamunur Rahman Malik; Arnaud Fontanet; Simon Cauchemez; ...
    Persistent Identifiers
    Publisher: Springer Science and Business Media LLC
    Project: ANR | INCEPTION (ANR-16-CONV-0005)

    International audience; Since its emergence in 2012, 2,260 cases and 803 deaths due to Middle East respiratory syndrome coronavirus (MERS-CoV) have been reported to the World Health Organization. Most cases were due to transmission in healthcare settings, sometimes caus...

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  • publication . Article . 2015
    Open Access English
    Authors:
    Anne Laure Pham-Hung d'Alexandry d'Orengiani; Lidia Duarte; Nicole Pavio; Sophie Le Poder;
    Publisher: HAL CCSD
    Project: ANR | EPICOREM (ANR-13-BSV3-0013)

    Highlights • Accessory proteins of coronaviruses play a role in virus adaptation to a new host. • Some FCoV harbour truncated gp3 proteins, an accessory protein peculiar of CCoV-I. • Deletions of gp3 do not influence their basic features. • Deletions impact the expressi...

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  • publication . Preprint . 2021
    English
    Authors:
    Gallic, Ewen; Lubrano, Michel; Michel, Pierre;
    Publisher: HAL CCSD
    Project: ANR | AMSE (EUR) (ANR-17-EURE-0020)

    Uprising in China, the global COVID-19 epidemic soon started to spread out in Europe. As no medical treatment was available, it became urgent to design optimal non-pharmaceutical policies. With the help of a SIR model, we contrast two policies, one based on herd immunit...

141 research outcomes, page 1 of 15