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42 research outcomes, page 1 of 5
  • publication . Article . Other literature type . 2013
    Open Access
    Authors:
    Arturo Galindo-Fraga; Ana A Ortiz-Hernández; Alejandra Ramírez-Venegas; Rafael Valdez Vázquez; Sarbelio Moreno-Espinosa; Beatriz Llamosas-Gallardo; Santiago Pérez-Patrigeon; Maggie Salinger; Laura Freimanis; Chiung Yu Huang; ...
    Persistent Identifiers
    Publisher: Elsevier BV

    Summary Background Influenza-like illnesses (ILI) are estimated to cause millions of deaths annually. Despite this disease burden, the etiologic causes of ILI are poorly described for many geographical regions. Methods Beginning in April 2010, we conducted an observatio...

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  • publication . Other literature type . Article . 2020
    Open Access English
    Authors:
    Blanca Taboada; Joel A. Vázquez-Pérez; José Esteban Muñoz-Medina; Pilar Ramos-Cervantes; Marina Escalera-Zamudio; Célia Boukadida; Alejandro Sanchez-Flores; Pavel Isa; Edgar Mendieta-Condado; José Arturo Martínez-Orozco; ...
    Persistent Identifiers
    Publisher: American Society for Microbiology

    The coronavirus disease 2019 (COVID-19) pandemic has affected most countries in the world. Studying the evolution and transmission patterns in different countries is crucial to enabling implementation of effective strategies for disease control and prevention. In this w...

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  • publication . Article . Other literature type . 2011
    Open Access
    Authors:
    Ana E. Gonzalez-Santiago; Luz A. Mendoza-Topete; Francisco Sánchez-Llamas; Rogelio Troyo-Sanromán; Carmen M. Gurrola-Díaz;
    Persistent Identifiers
    Publisher: Wiley

    Lung cancer is a malignant disease with increasing mortality rates. Cytokines play a role in normal cell growth regulation and differentiation and are also implicated in malignant disease. Among these cytokines, Transforming Growth Factor β type 1 (TGF‐β1) acts as a tum...

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  • publication . Other literature type . Article . 2011
    Open Access English
    Authors:
    Trujillo-Alonso, V.; Maruri-Avidal, L.; Arias, C. F.; Lopez, S.;
    Persistent Identifiers
    Publisher: American Society for Microbiology

    The unfolded protein response (UPR) is a cellular mechanism that is triggered in order to cope with the stress caused by the accumulation of misfolded proteins in the endoplasmic reticulum (ER). This response is initiated by the endoribonuclease inositol-requiring enzym...

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  • publication . Article . Other literature type . 2014
    Open Access
    Authors:
    Naccache, Samia N.; Federman, Scot; Veeraraghavan, Narayanan; Zaharia, Matei; Lee, Deanna; Samayoa, Erik; Bouquet, Jerome; Greninger, Alexander L.; Luk, Ka-Cheung; Enge, Barryett; ...
    Persistent Identifiers
    Publisher: Cold Spring Harbor Laboratory

    Unbiased next-generation sequencing (NGS) approaches enable comprehensive pathogen detection in the clinical microbiology laboratory and have numerous applications for public health surveillance, outbreak investigation, and the diagnosis of infectious diseases. However,...

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  • publication . Other literature type . Article . 2011
    Open Access English
    Authors:
    Michael O. Griffin; Guillermo Ceballos; Francisco Villarreal;
    Persistent Identifiers

    Tetracyclines were developed as a result of the screening of soil samples for antibiotics. The first(t) of these compounds, chlortetracycline, was introduced in 1947. Tetracyclines were found to be highly effective against various pathogens including rickettsiae, as wel...

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  • publication . Other literature type . Article . 2020
    Open Access English
    Authors:
    Zhikang Ye; Ying Wang; Luis Enrique Colunga-Lozano; Manya Prasad; Wimonchat Tangamornsuksan; Bram Rochwerg; Liang Yao; Shahrzad Motaghi; Rachel Couban; Maryam Ghadimi; ...
    Persistent Identifiers
    Publisher: Joule Inc.

    Background: Very little direct evidence exists on use of corticosteroids in patients with coronavirus disease 2019 (COVID-19). Indirect evidence from related conditions must therefore inform inferences regarding benefits and harms. To support a guideline for managing CO...

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  • publication . Article . Other literature type . 2015
    Open Access
    Authors:
    Liliana Sánchez-Tacuba; Margarito Rojas; Carlos F. Arias; Susana López;
    Persistent Identifiers
    Publisher: American Society for Microbiology

    ABSTRACT The innate immune response is the first line of defense of the host cell against a viral infection. In turn, viruses have evolved a wide variety of strategies to hide from, and to directly antagonize, the host innate immune pathways. One of these pathways is th...

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  • publication . Part of book or chapter of book . Other literature type . 2017
    Open Access
    Authors:
    Manuel Llano; Mario A. Peña-Hernandez;
    Persistent Identifiers
    Publisher: Elsevier
    Project: NIH | Role of PARP-1 in HIV-1 l... (5SC1GM115240-06)

    Abstract Viruses are obligate parasites that depend on cellular factors for replication. Pharmacological inhibition of essential viral proteins, mostly enzymes, is an effective therapeutic alternative in the absence of effective vaccines. However, this strategy commonly...

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  • publication . Article . Other literature type . Preprint . 2019
    Open Access
    Authors:
    Ramirez, Romel Rosales; Ludert, Juan E.;
    Publisher: American Society for Microbiology

    ABSTRACTDengue virus (DENV) is a mosquito-borne virus of the familyFlaviviridae.The RNA viral genome encodes for a polyprotein that is co-translationally processed into three structural proteins and seven non-structural proteins. The non-structural protein 1 (NS1) is a ...

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42 research outcomes, page 1 of 5