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360 research outcomes, page 1 of 36
  • publication . Article . 2014
    Open Access English
    Authors:
    Horm, Srey Viseth; Mardy, Sek; Rith, Sareth; Ly, Sovann; Heng, Seng; Vong, Sirenda; Kitsutani, Paul; Ieng, Vannra; Tarantola, Arnaud; Ly, Sowath; ...
    Persistent Identifiers
    Publisher: Public Library of Science

    Background The Cambodian National Influenza Center (NIC) monitored and characterized circulating influenza strains from 2009 to 2011. Methodology/Principal Findings Sentinel and study sites collected nasopharyngeal specimens for diagnostic detection, virus isolation, an...

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  • publication . Article . Other literature type . 2011
    Open Access English
    Authors:
    Kudelko M; Jb, Brault; Kwok K; My, Li; Pardigon N; Js, Peiris; Bruzzone R; Desprès P; Beatrice Nal; Pg, Wang;
    Persistent Identifiers
    Publisher: HAL CCSD

    International audience; Identification and characterization of virus-host interactions are very important steps towards a better comprehension of the molecular mechanisms responsible for disease progression and pathogenesis. To date, very few cellular factors involved i...

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  • publication . Article . Other literature type . 2018
    Open Access English
    Authors:
    Bourgarel, Mathieu; Pfukenyi, Davies M.; Boué, Vanina; Talignani, Loïc; Chiweshe, Ngoni; Diop, Fodé; Caron, Alexandre; Matope, Gift; Missé, Dorothée; Liégeois, Florian;
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: ANR | TIMTAMDEN (ANR-14-CE14-0029)

    Highlights • Coronavirus and Paramyxovirus circulate in Hipposideros bat species in Zimbabwe. • Importance of widening viral screening in under-investigated countries • Sentinel surveillance in sites with high zoonotic transmission potential

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  • publication . Article . 2010
    Open Access English
    Authors:
    Duval, Xavier; Van Der Werf, Sylvie; Blanchon, Thierry; Mosnier, Anne; Bouscambert-Duchamp, Maude; Tibi, Annick; Enouf, Vincent; Charlois-Ou, Cécile; Vincent, Corine; Andreoletti, Laurent; ...
    Persistent Identifiers
    Publisher: Public Library of Science

    Editors' Summary Background In the last few years, use of the neuraminidase inhibitors, oseltamivir and zanamivir, has been considered a key strategy for limiting the impact of influenza both in individuals (by reducing morbidity and mortality) and collectively (by slow...

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  • publication . Article . 2015
    Open Access English
    Authors:
    Romain Fragnoud; Marie Flamand; Frederic Reynier; Philippe Buchy; Vasna Duong; Alexandre Pachot; Gláucia Paranhos-Baccalà; Frederic Bedin;
    Persistent Identifiers
    Publisher: HAL CCSD

    Background Dengue is the most widespread mosquito-borne viral disease of public health concern. In some patients, endothelial cell and platelet dysfunction lead to life-threatening hemorrhagic dengue fever or dengue shock syndrome. Prognostication of disease severity is...

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  • publication . Article . Other literature type . 2015
    Open Access
    Authors:
    Changqing Li; Jaime Guillén; Nadia Rabah; Alexandre Blanjoie; Françoise Debart; Jean-Jacques Vasseur; Bruno Canard; Etienne Decroly; Bruno Coutard;
    Persistent Identifiers

    <jats:title>ABSTRACT</jats:title><jats:p>Alphaviruses are known to possess a unique viral mRNA capping mechanism involving the viral nonstructural protein nsP1. This enzyme harbors methyltransferase (MTase) and nsP1 guanylylation (GT) activities catalyzing the transfer ...

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  • publication . Article . 2020
    Open Access English
    Authors:
    Smadja, David M.; Guerin, Coralie L.; Chocron, Richard; Yatim, Nader; Boussier, Jeremy; Gendron, Nicolas; Khider, Lina; Hadjadj, Jérôme; Goudot, Guillaume; Debuc, Benjamin; ...
    Persistent Identifiers
    Publisher: HAL CCSD

    Background Coronavirus disease-2019 (COVID-19), a respiratory disease has been associated with ischemic complications, coagulation disorders, and an endotheliitis. Objectives To explore endothelial damage and activation-related biomarkers in COVID-19 patients with crite...

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  • publication . Article . Other literature type . 2019
    Open Access English
    Authors:
    Park, Young-Jun; Walls, Alexandra C.; Wang, Zhaoqian; Sauer, Maximillian M.; Li, Wentao; Tortorici, M. Alejandra; Bosch, Berend-Jan; DiMaio, Frank; Veesler, David;
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: NIH | Structural Studies of Cor... (5R01GM120553-03)

    The Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe and often lethal respiratory illness in humans, and no vaccines or specific treatments are available. Infections are initiated via binding of the MERS-CoV spike (S) glycoprotein to sialosides and ...

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  • publication . Article . Other literature type . 2018
    Open Access English
    Authors:
    Park, Young-Jun; Lacourse, Kaitlyn D.; Cambillau, Christian; DiMaio, Frank; Mougous, Joseph D.; Veesler, David;
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: NIH | Protein structure determi... (1R01GM123089-01)

    Type VI secretion systems (T6SSs) translocate effectors into target cells and are made of a contractile sheath and a tube docked onto a multi-protein transmembrane complex via a baseplate. Although some information is available about the mechanisms of tail contraction l...

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  • publication . Article . 2006
    Open Access English
    Authors:
    Lavillette, Dimitri; Barbouche, Rym; Yao, Yongxiu; Boson, Bertrand; Cosset, François-Loïc; Jones, Ian M; Fenouillet, Emmanuel;
    Publisher: HAL CCSD

    The capacity of the surface glycoproteins of enveloped viruses to mediate virus/cell binding and membrane fusion requires a proper thiol/disulfide balance. Chemical manipulation of their redox state using reducing agents or free sulfhydryl reagents affects virus/cell in...

360 research outcomes, page 1 of 36