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23 research outcomes, page 1 of 3
  • publication . Article . 2012
    Open Access English
    Authors:
    Richard Njouom; Elsie Laban Yekwa; Pierre Cappy; Astrid Vabret; Pascal Boisier; Dominique Rousset;
    Persistent Identifiers
    Publisher: Oxford University Press

    Abstract Background. No information is available on the viral etiology of upper respiratory tract infections in Cameroon. Methods. We prospectively enrolled outpatients with influenza-like illness (ILI) presenting at 14 sentinel clinics located across the country from J...

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  • publication . Article . 2017
    Open Access
    Authors:
    Reina S. Sikkema; Elmoubasher Farag; Sayed Himatt; Adel K Ibrahim; Hamad Al-Romaihi; Salih A. Al-Marri; Mohamed Al-Thani; Ahmed M. El-Sayed; Mohammed Al-Hajri; Bart L. Haagmans; ...
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)
    Project: EC | COMPARE (643476), EC | PREPARE (602525)

    Abstract The transmission routes and risk factors for zoonotic Middle East respiratory syndrome coronavirus (MERS-CoV) infections are still unknown. We used the World Health Organization questionnaire for MERS-CoV case-control studies to assess risk factors for human ME...

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  • publication . Article . 2018
    Open Access English
    Authors:
    Patience K. Kiyuka; Charles N. Agoti; Patrick K. Munywoki; Regina Njeru; Anne Bett; James R. Otieno; Grieven P Otieno; Everlyn Kamau; Taane G. Clark; László van den Hoek; ...
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)
    Project: UKRI | The interactions between ... (MR/K000551/1), UKRI | Understanding the transmi... (MR/N010469/1), UKRI | Zika: Zika virus surveill... (MC_PC_15103), UKRI | Geographic genetic profil... (MR/M01360X/1), WT | Defining pathways of resp... (102975)

    Infections with human coronavirus NL63 are common and reinfections occur repeatedly throughout life. A subset of repeat infections show enhanced virus replication with no evidence of genotype switching, indicating that initial exposure is insufficient to elicit a protec...

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  • publication . Article . 2006
    Open Access English
    Authors:
    Luan-Yin Chang; Bor-Luen Chiang; Chuan-Liang Kao; Mei-Hwan Wu; Pei-Jer Chen; Ben Berkhout; Hui-Ching Yang; Li-Min Huang;
    Persistent Identifiers

    Abstract We investigated whether infection with a novel human coronavirus (HCoV), called “New Haven coronavirus” (HCoV-NH)—which is similar to and likely represents the same species as another novel HCoV, HCoV-NL63—is associated with Kawasaki disease (KD) in Taiwan. Fif...

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  • publication . Article . Other literature type . 2010
    Open Access
    Authors:
    Barry Rockx; Eric F. Donaldson; Matthew B. Frieman; Timothy P. Sheahan; Davide Corti; Antonio Lanzavecchia; Ralph S. Baric;
    Publisher: Oxford University Press (OUP)
    Project: NIH | SARS Reverse Genetics (5R01AI059136-03), NIH | Developing Vaccine Candid... (3P01AI059443-03S1)

    markdownabstractBackground. Severe acute respiratory syndrome (SARS) emerged as a human disease in 2002. Detailed phylogenetic analysis and epidemiologic studies have suggested that the SARS Coronavirus (SARS-CoV) originated from animals. The spike (S) glycoprotein has ...

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  • publication . Article . 2020
    Open Access
    Authors:
    de Nooijer, Aline H; Grondman, Inge; Janssen, Nico A F; Netea, Mihai G; Willems, Loek; van de Veerdonk, Frank L; Giamarellos-Bourboulis, Evangelos J; Toonen, Erik J M; Joosten, Leo A B; Jaeger, Martin; ...
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)

    Abstract Background Excessive activation of immune responses in coronavirus disease 2019 (COVID-19) is considered to be related to disease severity, complications, and mortality rate. The complement system is an important component of innate immunity and can stimulate i...

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  • publication . Preprint . Article . 2020
    Open Access
    Authors:
    Gerco den Hartog; Rutger M. Schepp; Marjan Kuijer; Corine H. GeurtsvanKessel; Josine van Beek; Nynke Y. Rots; Marion Koopmans; Fiona R. M. van der Klis; Robert S. van Binnendijk;
    Publisher: Cold Spring Harbor Laboratory

    Detection of SARS-CoV-2–specific antibodies is instrumental to study seroprevalence and immune protection to the virus. We validated a multiplex assay to detect antibodies to SARS-CoV-2 N, S1, and RBD, and provide a framework to perform accurate serosurveys for COVID-19...

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  • publication . Article . 2005
    Open Access English
    Authors:
    Lia van der Hoek; Ben Berkhout;
    Persistent Identifiers
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  • publication . Article . 2018
    Open Access
    Authors:
    Nicole A. Hoff; Patrick Mukadi; Reena H. Doshi; Matthew S. Bramble; Kai Lu; Adva Gadoth; Cyrus Sinai; D’Andre Spencer; Bradley Nicholson; Russell A. Williams; ...
    Persistent Identifiers
    Publisher: eScholarship, University of California
    Project: NIH | University of California ... (5D43TW009343-07), NIH | Serological prevalence of... (5R21AI107420-02)

    Healthcare workers in an area with a previous Ebola outbreak in the Democratic Republic of the Congo exhibited both antibody response and neutralizing capacity to at least 1 Ebola protein, despite never having been diagnosed with Ebola virus disease.

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  • publication . Article . Preprint . 2020
    Open Access English
    Authors:
    Eelke Brandsma; Han J.M.P. Verhagen; Thijs J.W. van de Laar; Eric C. J. Claas; Marion Cornelissen; Emile van den Akker;
    Persistent Identifiers
    Publisher: Oxford University Press

    <jats:title>Abstract</jats:title><jats:p>Recent advances in CRISPR-based diagnostics suggest that DETECTR, a combination of isothermal reverse transcriptase loop mediated amplification (RT-LAMP) and subsequent Cas12 bystander nuclease activation by amplicon targeting ri...

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23 research outcomes, page 1 of 3