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19 research outcomes, page 1 of 2
  • publication . Article . 2015
    Open Access English
    Authors:
    Clément Cocita; Rachel Guiton; Gilles Bessou; Lionel Chasson; Marilyn Boyron; Karine Crozat; Marc Dalod;
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: ANR | Amidex (ANR-11-IDEX-0001), ANR | PSL (ANR-10-IDEX-0001)

    In mice, plasmacytoid dendritic cells (pDC) and natural killer (NK) cells both contribute to resistance to systemic infections with herpes viruses including mouse Cytomegalovirus (MCMV). pDCs are the major source of type I IFN (IFN-I) during MCMV infection. This respons...

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  • publication . Article . 2015
    Open Access English
    Authors:
    Stéphane Priet; Audrey Lartigue; Françoise Debart; Jean-Michel Claverie; Chantal Abergel;
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: ANR | Pandoravirus (ANR-14-CE14-0023)

    <jats:title>Abstract</jats:title> <jats:p>Giant viruses from the Mimiviridae family replicate entirely in their host cytoplasm where their genes are transcribed by a viral transcription apparatus. mRNA polyadenylation uniquely occurs at hairpin-forming palindromic seque...

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  • publication . Other literature type . Article . Preprint . 2020
    Open Access
    Authors:
    Christelle Baunez; Mickael Degoulet; Stephane Luchini; Patrick A. Pintus; Miriam Teschl;
    Publisher: Cold Spring Harbor Laboratory
    Project: ANR | AMSE (EUR) (ANR-17-EURE-0020)

    <jats:title>Abstract</jats:title><jats:p>This note provides an early assessment of the reinforced measures to curb the COVID-19 pandemic in France, which include a curfew of selected areas and culminate in a second COVID-19-related lock-down that started on October 30, ...

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  • publication . Article . 2020
    Open Access English
    Authors:
    Pauline Maisonnasse; Jeremie Guedj; Vanessa Contreras; Sylvie Behillil; Caroline Solas; Romain Marlin; Thibaut Naninck; Andrés Pizzorno; Julien Lemaitre; Antonio Gonçalves; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | TRANSVAC2 (730964), ANR | IDMIT (ANR-11-INBS-0008), EC | EVAg (653316), EC | Fight-nCoV (101003555)

    International audience; Coronavirus disease 2019 (COVID-19) has rapidly become a global pandemic and no antiviral drug or vaccine is yet available for the treatment of this disease1-3. Several clinical studies are ongoing to evaluate the efficacy of repurposed drugs tha...

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  • publication . Article . Other literature type . 2021
    Open Access English
    Authors:
    Jacques Piazzola; William Bruch; Christelle Desnues; Philippe Parent; Christophe Yohia; Elisa Canepa;
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: ANR | MATRAC (ANR-18-ASTR-0002)

    International audience; Human behaviors probably represent the most important causes of the SARS-Cov-2 virus propagation. However, the role of virus transport by aerosols—and therefore the influence of atmospheric conditions (temperature, humidity, type and concentratio...

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  • publication . Preprint . Article . 2020
    Open Access English
    Authors:
    Christelle Baunez; Mickael Degoulet; Stéphane Luchini; Patrick A. Pintus; Miriam Teschl;
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: ANR | AMSE (EUR) (ANR-17-EURE-0020)

    International audience; Tests are crucial to know about the number of people who have fallen ill with COVID-19 and to understand in real-time whether the dynamics of the pandemic is accelerating or decelerating. But tests are a scarce resource in many countries. The key...

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  • publication . Article . 2016
    Open Access English
    Authors:
    Livio Bioglio; Mathieu Génois; Christian L. Vestergaard; Chiara Poletto; Alain Barrat; Vittoria Colizza;
    Persistent Identifiers
    Publisher: BioMed Central
    Project: EC | MULTIPLEX (317532), ANR | Amidex (ANR-11-IDEX-0001), ANR | HarMS-flu (ANR-12-MONU-0018), EC | PREDEMICS (278433)

    Background The homogeneous mixing assumption is widely adopted in epidemic modelling for its parsimony and represents the building block of more complex approaches, including very detailed agent-based models. The latter assume homogeneous mixing within schools, workplac...

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  • publication . Article . 2020
    Open Access English
    Authors:
    Fawaz Alzaid; Jean-Baptiste Julla; Marc Diedisheim; Charline Potier; Louis Potier; Gilberto Velho; Bénédicte Gaborit; Philippe Manivet; Stéphane Germain; Tiphaine Vidal-Trecan; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: ANR | MitoFLAME (ANR-19-CE14-0005), EC | EpiFAT (725790)

    International audience; Early in the COVID-19 pandemic, type 2 diabetes (T2D) was marked as a risk factor for severe disease and mortality. Inflammation is central to the aetiology of both conditions where variations in immune responses can mitigate or aggravate disease...

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  • publication . Other literature type . Article . Preprint . 2020
    Open Access
    Authors:
    S. Edouard; P. Colson; C. Melenotte; F. De Pinto; L. Thomas; B. La Scola; M. Million; H. Tissot-Dupont; P. Gautret; Andreas Stein; ...
    Publisher: Cold Spring Harbor Laboratory
    Project: ANR | MHT (ANR-15-CE36-0004)

    An indirect in-house immunofluorescent assay was developed in order to assess the serological status of COVID-19 patients in Marseille, France. Performance of IFA was compared to a commercial ELISA IgG kit. We tested 888 RT-qPCR-confirmed COVID-19 patients (1302 serum s...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Carrat F; Touvier M; Severi G; Meyer L; Jusot F; Lapidus N; Rahib D; Lydié N; Marie Aline Charles; Ancel P; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: ANR | CONSTANCES (ANR-11-INBS-0002)

    <jats:title>Abstract</jats:title><jats:sec> <jats:title>Background</jats:title> <jats:p>Our main objectives were to estimate the incidence of illnesses presumably caused by SARS-CoV-2 infection during the lockdown period and to identify the associated risk factors.</jat...

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19 research outcomes, page 1 of 2