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235 research outcomes, page 1 of 24
  • publication . Article . Other literature type . 2016
    Open Access
    Authors:
    David M. Morens; Anthony S. Fauci;
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)
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  • publication . Article . 2020
    Open Access English
    Authors:
    Lo, Michael K; Spengler, Jessica R; Krumpe, Lauren R H; Welch, Stephen R; Chattopadhyay, Anasuya; Harmon, Jessica R; Coleman-McCray, Joann D; Scholte, Florine E M; Hotard, Anne L; Fuqua, Joshua L; ...
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)

    Abstract Nipah virus (NiV) is a highly pathogenic zoonotic paramyxovirus that causes fatal encephalitis and respiratory disease in humans. There is currently no approved therapeutic for human use against NiV infection. Griffithsin (GRFT) is high-mannose oligosaccharide ...

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  • publication . Article . Other literature type . 2018
    Open Access English
    Authors:
    Mathieu, Cyrille; Porotto, Matteo; Figueira, Tiago N; Horvat, Branka; Moscona, Anne;
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: NIH | MOLECULAR BASIS FOR PARAI... (5R29AI031971-03), NIH | Design of CNS-targeted pe... (5R33AI101333-04), ANR | ECOFECT (ANR-11-LABX-0048), NIH | Engineering protease-resi... (5R01AI114736-04), ANR | Avenir L.S.E. (ANR-11-IDEX-0007)

    International audience; Background. The emerging zoonotic paramyxovirus Nipah virus (NiV) causes severe respiratory and neurological disease inhumans, with high fatality rates. Nipah virus can be transmitted via person-to-person contact, posing a high risk for epidemic ...

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  • publication . Article . 1986
    Open Access English
    Authors:
    Ronald B. Turner; Alma Felton; Kenneth M. Kosak; Douglas K. Kelsey; Carlton K. Meschievitz;
    Persistent Identifiers
    Publisher: The University of Chicago Press

    Fifty-five volunteers treated with either intranasal recombinant interferon (rIFN; 2 X 10(6) IU/day) or placebo for 15 days were exposed to coronavirus by direct intranasal inoculation on the eighth day of treatment. Symptom scores were recorded, and cultures of virus w...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Joshua M. Thiede; Abigail R. Gress; Samuel D Libby; Christine E. Ronayne; William E. Matchett; Brooke Noren; Joanne L Billings; Vineet D. Menachery; Ryan A. Langlois; Susan Kline; ...
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)

    Abstract Coronavirus disease 2019 (COVID-19) outcomes are linked to host immune responses and may be affected by antiviral therapy. We investigated antibody and cytokine responses in ACTT-1 study participants enrolled at our center. We studied serum specimens from 19 ho...

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  • publication . Article . 2005
    Open Access
    Authors:
    Frank Esper; Eugene D. Shapiro; Carla Weibel; David Ferguson; Marie L. Landry; Jeffrey S. Kahn;
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)

    Abstract Kawasaki disease is a systemic vasculitis of childhood; its etiology is unknown. We identified evidence of a novel human coronavirus, designated “New Haven coronavirus” (HCoVNH), in respiratory secretions from a 6-month-old infant with classic Kawasaki disease....

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  • publication . Article . 2021
    Open Access
    Authors:
    Sumathi Sivapalasingam; George A Saviolakis; Kirsten Kulcsar; Aya Nakamura; Thomas Conrad; Mohamed Hassanein; Giane Sumner; Chinnasamy Elango; M.A. Kamal; Simon Eng; ...
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)

    REGN3048 and REGN3051 in combination were well tolerated. Each monoclonal antibody displayed pharmacokinetics expected of human IgG1 antibodies; it was not immunogenic. Clinical and preclinical data support further development of REGN3048 and REGN3051 for the treatment ...

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  • publication . Article . Other literature type . 2011
    Open Access
    Authors:
    John V. Williams; James E. Crowe;
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)

    To the Editor—We thank Schlapbach et al for their comments on our recent prospective study of human metapneumovirus (HMPV) in hospitalized children. Schlapbach and colleagues describe a fatal case of acute respiratory distress syndrome (ARDS) attributed to HMPV and refe...

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  • publication . Article . Other literature type . 2014
    Open Access
    Authors:
    Monto, A. S.; Malosh, R. E.; Petrie, J. G.; Thompson, M. G.; Ohmit, S. E.;
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)

    Acute respiratory infections are the most common cause of symptomatic illness in the general population. As a result, they have been studied often over the past century, first in terms of their frequency and characteristics and then, in the last 50 years, their etiology...

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  • publication . Article . Other literature type . 2010
    Open Access English
    Authors:
    Lau, Lincoln L. H.; Cowling, Benjamin J.; Fang, Vicky J.; Chan, Kwok‐Hung; Lau, Eric H. Y.; Lipsitch, Marc; Cheng, Calvin K. Y.; Houck, Peter M.; Uyeki, Timothy M.; Peiris, J. S. Malik; ...
    Persistent Identifiers
    Publisher: Oxford University Press. The Journal's web site is located at http://jid.oxfordjournals.org
    Project: NIH | MIDAS Center for Communic... (1U54GM088558-01), NIH | A Controlled Trial of Mas... (5U01CI000439-02)

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235 research outcomes, page 1 of 24