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23 research outcomes, page 1 of 3
  • publication . Article . Other literature type . 2015
    Open Access
    Authors:
    Viktoriya Borisevich; Benhur Lee; Andrew C. Hickey; Blair L. DeBuysscher; Christopher C. Broder; Heinz Feldmann; Barry Rockx;
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)
    Project: NIH | Nipah Virus and Hendra Vi... (5R01AI054715-03)

    textabstractHenipaviruses are zoonotic viruses that can cause severe and acute respiratory diseases and encephalitis in humans. To date, no vaccine or treatments are approved for human use. The presence of neutralizing antibodies is a strong correlate of protection agai...

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  • publication . Other literature type . Article . 2012
    Open Access English
    Authors:
    Sander Herfst; Albert D. M. E. Osterhaus; Ron A. M. Fouchier;
    Persistent Identifiers
    Publisher: Oxford University Press

    Recently, we and others obtained experimental evidence that highly pathogenic avian influenza virus subtype H5 can acquire the ability to transmit via aerosols between ferrets. Upon submission of manuscripts describing the results of these studies, the US National Scien...

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  • publication . Article . Other literature type . 2005
    Open Access
    Authors:
    Chisato Shimizu; Hiroko Shike; Susan C. Baker; Francesca L. Garcia; Lia van der Hoek; Taco W. Kuijpers; Sharon L. Reed; Anne H. Rowley; Stanford T. Shulman; Helen Talbot; ...
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)
    Project: NIH | Genetic Influences &Gene ... (1R01HL069413-01), NIH | STRUCTURE AND FUNCTION OF... (1R01AI045798-01A2)

    Kawasaki disease (KD) is a self-limited, systemic vasculitis of children for which an infectious trigger is suspected. Recently, an association between KD and human coronavirus ( HCoV) - New Haven (NH) was reported, on the basis of polymerase chain reaction (PCR) with p...

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  • publication . Article . 2020
    Open Access English
    Authors:
    Eelke Brandsma; Han J.M.P. Verhagen; Thijs J.W. van de Laar; Eric C. J. Claas; Marion Cornelissen; Emile van den Akker;
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)

    Abstract Background Recent advances in CRISPR-based diagnostics suggest that DETECTR, a combination of reverse-transcriptase loop-mediated isothermal amplification (RT-LAMP) and subsequent Cas12 bystander nuclease activation by amplicon-targeting ribonucleoprotein comp...

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  • publication . Article . 2014
    Open Access English
    Authors:
    Falsey, Ann; McElhaney, Janet; Beran, Jiri; van Essen, Gerrit; Duval, Xavier; Esen, Meral; Galtier, Florence; Gervais, Pierre; Hwang, Shinn-Jang; Kremsner, Peter; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: CIHR

    International audience; Background. Few studies have prospectively assessed viral etiologies of acute respiratory infections in community-based elderly individuals. We assessed viral respiratory pathogens in individuals ≥65 years with influenza-like illness (ILI).Method...

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  • publication . Article . 2017
    Open Access English
    Authors:
    Rimoin, Anne W; Lu, Kai; Bramble, Matthew S; Steffen, Imke; Doshi, Reena H; Hoff, Nicole A; Mukadi, Patrick; Nicholson, Bradly P; Alfonso, Vivian H; Olinger, Gerrard; ...
    Persistent Identifiers
    Publisher: Oxford University Press
    Project: NIH | University of California ... (5D43TW009343-07), NIH | Serological prevalence of... (5R21AI107420-02)

    Duration of immunity against Ebola virus among survivors remains unclear. We assessed serological immune profiles and retention of Ebola virus neutralizing antibodies in 14 survivors of the 1976 Yambuku outbreak 40 years postinfection, providing the longest documentatio...

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  • publication . Article . 2004
    Open Access
    Authors:
    Leontine J. R. van Elden; Anton M. van Loon; Floris Van Alphen; Karin A. W. Hendriksen; Andy I. M. Hoepelman; Marian G. J. van Kraaij; Jan Jelrik Oosterheert; P. Schipper; Rob Schuurman; Monique Nijhuis;
    Persistent Identifiers

    During the past years, human coronaviruses (HCoVs) have been increasingly identified as pathogens associated with more-severe respiratory tract infection (RTI). Diagnostic tests for HCoVs are not frequently used in the routine setting. It is likely that, as a result, th...

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  • publication . Article . 2017
    Open Access English
    Authors:
    Reina S. Sikkema; Elmoubasher Farag; Sayed Himatt; Adel K Ibrahim; Hamad Al-Romaihi; Salih A. Al-Marri; Mohamed Al-Thani; Ahmed M. El-Sayed; Mohammed Al-Hajri; Bart L. Haagmans; ...
    Persistent Identifiers
    Publisher: Oxford University Press
    Project: EC | PREPARE (602525), EC | COMPARE (643476)

    Abstract The transmission routes and risk factors for zoonotic Middle East respiratory syndrome coronavirus (MERS-CoV) infections are still unknown. We used the World Health Organization questionnaire for MERS-CoV case-control studies to assess risk factors for human ME...

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  • publication . Article . 2018
    Open Access English
    Authors:
    Kiyuka, Patience K.; Agoti, Charles N.; Munywoki, Patrick K.; Njeru, Regina; Bett, Anne; Otieno, James R.; Otieno, Grieven P.; Kamau, Everlyn; Clark, Taane G.; van der Hoek, Lia; ...
    Persistent Identifiers
    Project: UKRI | Understanding the transmi... (MR/N010469/1), UKRI | The interactions between ... (MR/K000551/1), UKRI | Zika: Zika virus surveill... (MC_PC_15103), UKRI | Geographic genetic profil... (MR/M01360X/1), WT | Defining pathways of resp... (102975)

    Infections with human coronavirus NL63 are common and reinfections occur repeatedly throughout life. A subset of repeat infections show enhanced virus replication with no evidence of genotype switching, indicating that initial exposure is insufficient to elicit a protec...

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  • publication . Article . 2006
    Open Access English
    Authors:
    Luan-Yin Chang; Bor-Luen Chiang; Chuan-Liang Kao; Mei-Hwan Wu; Pei-Jer Chen; Ben Berkhout; Hui-Ching Yang; Li-Min Huang;
    Persistent Identifiers

    Abstract We investigated whether infection with a novel human coronavirus (HCoV), called “New Haven coronavirus” (HCoV-NH)—which is similar to and likely represents the same species as another novel HCoV, HCoV-NL63—is associated with Kawasaki disease (KD) in Taiwan. Fif...

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23 research outcomes, page 1 of 3