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527 research outcomes, page 1 of 53
  • publication . Article . 2005
    Open Access
    Authors:
    Yu Chih Liu; Vicky Huang; Ti Chun Chao; Chwan-Deng Hsiao; Atsui Lin; Ming-Fu Chang; Lu-Ping Chow;
    Persistent Identifiers
    Publisher: Elsevier BV

    SARS-CoV 3CL protease is essential for viral protein processing and is regarded as a good drug target to prevent SARS-CoV replication. In the present study, we established a high-throughput FRET technique for screening for anti-SARS-CoV 3CL protease drugs. Of a thousand...

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  • publication . Article . Other literature type . Preprint . 2020
    Open Access English
    Authors:
    Ivan T. Lee; Tsuguhisa Nakayama; Chien Ting Wu; Yury Goltsev; Sizun Jiang; Phillip A. Gall; Chun-Kang Liao; Liang Chun Shih; Christian M. Schürch; David R. McIlwain; ...
    Persistent Identifiers
    Publisher: Cold Spring Harbor Laboratory

    <jats:p>We investigated the expression and subcellular localization of the SARS-CoV-2 receptor, angiotensin-converting enzyme 2 (ACE2), within the upper (nasal) and lower (pulmonary) respiratory tracts of healthy human donors. We detected ACE2 protein expression within ...

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  • publication . Article . 2005
    Open Access English
    Authors:
    Cheng Hua Lee; Nicole Huang; Hong Jen Chang; Yea-Jen Hsu; Mei Chu Wang; Yiing-Jenq Chou;
    Persistent Identifiers
    Publisher: BMC

    <p>Abstract</p> <p>Background</p> <p>When an emerging infectious disease like severe acute respiratory syndrome (SARS) strikes suddenly, many wonder the public's overwhelming fears of SARS may deterred patients from seeking routine care from hospitals and/or interrupt p...

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  • publication . Article . 2017
    Open Access English
    Authors:
    Ya Min Yang; Chen Yang Hsu; Chao Chih Lai; Ming Fang Yen; Paul S. Wikramaratna; Hsiu Hsi Chen; Tsung Hsi Wang;
    Persistent Identifiers
    Publisher: Nature Publishing Group

    Abstract To date, 1841 cases of Middle East respiratory syndrome coronavirus (MERS-CoV) infection have been reported worldwide, with 652 deaths. We used a publically available case line list to explore the effect of relevant factors, notably underlying comorbidities, on...

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  • publication . Article . 2016
    Open Access
    Authors:
    Sheng-Der Hsu; Cheng-Jueng Chen; Wei-Kuo Chang; Yih-Jin Hu;
    Persistent Identifiers
    Publisher: Public Library of Science (PLoS)

    The Postgraduate Year (PGY) Program allows doctors-in-training to learn about the diagnosis, treatment and nursing of various common, general diseases. These items form the core curriculum and are mostly learned through caring for patients and clinical teaching. Doctors...

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  • publication . Article . 2009
    Open Access English
    Authors:
    Yu-Tung Huang; Yue-Chune Lee; Chun-Ju Hsiao;
    Publisher: Formosan Medical Association & Elsevier. Published by Elsevier (Singapore) Pte Ltd

    Background/Purpose: In 2003, the severe acute respiratory syndrome (SARS) outbreak resulted in 8096 probable cases and 774 deaths in 26 countries. The purpose of this study was to explore the effect of the SARS outbreak on hospitalization for chronic ambulatory-care-sen...

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  • publication . Preprint . Other literature type . 2020
    Open Access English
    Authors:
    Achraf Ammar; Michael Brach; Khaled Trabelsi; Hamdi Chtourou; Omar Boukhris; Liwa Masmoudi; Bassem Bouaziz; Ellen Bentlage; Daniella How; Mona Ahmed; ...
    Persistent Identifiers
    Publisher: HAL CCSD

    <jats:title>Abstract</jats:title><jats:sec><jats:title>Background</jats:title><jats:p>Public health recommendations and governmental measures during the COVID-19 pandemic have enforced numerous restrictions on daily living including social distancing, isolation and home...

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  • publication . Preprint . 2020
    Open Access English
    Authors:
    Ho, Yu-Chen; Chen, Yi-Hsuan; Hung, Shen-Hua; Huang, Chien-Hao; Po, Poga; Chan, Chung-Hsi; Yang, Di-Kai; Tu, Yi-Chin; Liu, Tyng-Luh; Fang, Chi-Tai;

    How to avoid a second wave of COVID-19 after reopening the economy is a pressing question. The extremely high basic reproductive number $R_0$ (5.7 to 6.4, shown in new studies) of SARS-CoV-2 further complicates the challenge. Here we assess effects of Social distancing ...

  • publication . Article . 2017
    Open Access
    Authors:
    Cheng-Wei Yang; Yue-Zhi Lee; Hsing-Yu Hsu; Chuan Shih; Yu-Sheng Chao; Hwan-You Chang; Shiow-Ju Lee;
    Persistent Identifiers
    Publisher: Springer Science and Business Media LLC

    Abstract Tylophorine-based compounds exert broad spectral, potent inhibition of coronaviruses. NF-κB activation is a common pro-inflammatory response of host cells to viral infection. The aims of this study were to (i) find an effective combination treatment for coronav...

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  • publication . Article . 2004
    Open Access
    Authors:
    Yee-Chun Chen; Ming-Fong Chen; Shuen-Zen Liu; James C. Romeis; Yuan-Teh Lee;
    Persistent Identifiers
    Publisher: Centers for Disease Control and Prevention (CDC)

    To the Editor: During the global epidemic of severe acute respiratory syndrome (SARS), the illness was transmitted rapidly within hospitals, which created pools of persons who became infected and through whom the disease was spread. Intrahospital transmission amplified ...

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527 research outcomes, page 1 of 53