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95 research outcomes, page 1 of 10
  • publication . Article . Other literature type . 2018
    Open Access English
    Authors:
    Cyrille Mathieu; Matteo Porotto; Tiago N. Figueira; Branka Horvat; Anne Moscona;
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: ANR | Avenir L.S.E. (ANR-11-IDEX-0007), NIH | Design of CNS-targeted pe... (5R33AI101333-04), NIH | Engineering protease-resi... (5R01AI114736-04), ANR | ECOFECT (ANR-11-LABX-0048), NIH | MOLECULAR BASIS FOR PARAI... (5R29AI031971-03)

    International audience; Background. The emerging zoonotic paramyxovirus Nipah virus (NiV) causes severe respiratory and neurological disease inhumans, with high fatality rates. Nipah virus can be transmitted via person-to-person contact, posing a high risk for epidemic ...

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  • publication . Other literature type . Article . 2015
    Open Access English
    Authors:
    Viktoriya Borisevich; Benhur Lee; Andrew C. Hickey; Blair L. DeBuysscher; Christopher C. Broder; Heinz Feldmann; Barry Rockx;
    Persistent Identifiers
    Publisher: Oxford University Press
    Project: NIH | Nipah Virus and Hendra Vi... (5R01AI054715-03)

    textabstractHenipaviruses are zoonotic viruses that can cause severe and acute respiratory diseases and encephalitis in humans. To date, no vaccine or treatments are approved for human use. The presence of neutralizing antibodies is a strong correlate of protection agai...

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  • publication . Article . Other literature type . 2010
    Open Access English
    Authors:
    Lincoln L. H. Lau; Benjamin J. Cowling; Vicky J. Fang; Kwok-Hung Chan; Eric H. Y. Lau; Marc Lipsitch; Calvin K. Y. Cheng; Peter M. Houck; Timothy M. Uyeki; J. S. Malik Peiris; ...
    Persistent Identifiers
    Publisher: Oxford University Press. The Journal's web site is located at http://jid.oxfordjournals.org
    Project: NIH | A Controlled Trial of Mas... (5U01CI000439-02), NIH | MIDAS Center for Communic... (1U54GM088558-01)

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  • publication . Article . Other literature type . 2017
    Open Access
    Authors:
    Chikara Ogimi; Alexander L. Greninger; Alpana Waghmare; Jane Kuypers; Ryan C. Shean; Hu Xie; Wendy M. Leisenring; Terry Stevens-Ayers; Keith R. Jerome; Janet A. Englund; ...
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)
    Project: NIH | Infections in Hematopoiet... (5K24HL093294-08), NIH | Viral and Host Biomarkers... (5K23AI114844-02), NIH | Targeting Alloreactivity ... (5P01CA018029-36)

    Background Recent data suggest that human coronavirus (HCoV) pneumonia is associated with significant mortality in hematopoietic cell transplant (HCT) recipients. Investigation of risk factors for prolonged shedding and intrahost genome evolution may provide critical in...

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  • publication . Article . 2015
    Open Access
    Authors:
    Florian Wrensch; Christina B. Karsten; Kerstin Gnirß; Markus Hoffmann; Kai Lu; Ayato Takada; Michael Winkler; Graham Simmons; Stefan Pöhlmann;
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)
    Project: NIH | Broad spectrum antivirals... (1R21AI107165-01)

    Ebolaviruses are highly pathogenic in humans and nonhuman primates and pose a severe threat to public health. The interferon-induced transmembrane (IFITM) proteins can restrict entry of ebolaviruses, influenza A viruses, and other enveloped viruses. However, the breadth...

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  • publication . Article . Other literature type . 2005
    Open Access
    Authors:
    Chisato Shimizu; Hiroko Shike; Susan C. Baker; Francesca L. Garcia; Lia van der Hoek; Taco W. Kuijpers; Sharon L. Reed; Anne H. Rowley; Stanford T. Shulman; Helen Talbot; ...
    Persistent Identifiers
    Project: NIH | Genetic Influences &Gene ... (1R01HL069413-01), NIH | STRUCTURE AND FUNCTION OF... (1R01AI045798-01A2)

    Kawasaki disease (KD) is a self-limited, systemic vasculitis of children for which an infectious trigger is suspected. Recently, an association between KD and human coronavirus ( HCoV) - New Haven (NH) was reported, on the basis of polymerase chain reaction (PCR) with p...

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  • publication . Article . Other literature type . 2016
    Open Access English
    Authors:
    Ingrid Peterson; Naor Bar-Zeev; Neil Kennedy; Antonia Ho; Laura Newberry; Miguel A. SanJoaquin; Mavis Menyere; Maaike Alaerts; Gugulethu Mapurisa; Moses Chilombe; ...
    Persistent Identifiers
    Project: WT , NIH | Institutional Collaborati... (3U01CK000146-05S1)

    Background:\ud We used data from 4 years of pediatric severe acute respiratory illness (SARI) sentinel surveillance in Blantyre, Malawi, to identify factors associated with clinical severity and coviral clustering.\ud \ud Methods:\ud From January 2011 to December 2014, ...

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  • publication . Article . Preprint . Other literature type . 2020
    Open Access English
    Authors:
    Marta Galanti; Jeffrey Shaman;
    Publisher: Oxford University Press (OUP)

    Abstract Background Although the mechanisms of adaptive immunity to pandemic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are still unknown, the immune response to the widespread endemic coronaviruses HKU1, 229E, NL63, and OC43 provide a useful reference...

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  • publication . Other literature type . Article . 2015
    Open Access English
    Authors:
    Kun Li; Christine L. Wohlford-Lenane; Stanley Perlman; Jincun Zhao; Alexander K. Jewell; Leah R. Reznikov; Katherine N. Gibson-Corley; David K. Meyerholz; Paul B. McCray;
    Persistent Identifiers
    Publisher: Oxford University Press
    Project: NIH | Animal Core (5P01AI060699-10), NIH | Administrative Core (3P30DK054759-15S1)

    Middle East respiratory syndrome coronavirus (MERS-CoV) causes life-threatening disease. Dipeptidyl peptidase 4 (DPP4) is the receptor for cell binding and entry. There is a need for small-animal models of MERS, but mice are not susceptible to MERS because murine dpp4 d...

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  • publication . Article . Other literature type . 2016
    Open Access
    Authors:
    Robert J. Fischer; Trenton Bushmaker; Seth D. Judson; Vincent J. Munster;
    Persistent Identifiers

    The largest outbreak of Ebola virus disease began in Gueckedou, Guinea, West Africa, in December 2013 and rapidly spread to major population centers in 3 West African countries. Early reports in some scientific and public media speculated that the virus had evolved to m...

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95 research outcomes, page 1 of 10