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16 research outcomes, page 1 of 2
  • publication . Other literature type . Article . 2015
    Open Access English
    Authors:
    Viktoriya Borisevich; Benhur Lee; Andrew C. Hickey; Blair L. DeBuysscher; Christopher C. Broder; Heinz Feldmann; Barry Rockx;
    Persistent Identifiers
    Publisher: Oxford University Press
    Project: NIH | Nipah Virus and Hendra Vi... (5R01AI054715-03)

    textabstractHenipaviruses are zoonotic viruses that can cause severe and acute respiratory diseases and encephalitis in humans. To date, no vaccine or treatments are approved for human use. The presence of neutralizing antibodies is a strong correlate of protection agai...

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  • publication . Article . Other literature type . 2005
    Open Access
    Authors:
    Chisato Shimizu; Hiroko Shike; Susan C. Baker; Francesca L. Garcia; Lia van der Hoek; Taco W. Kuijpers; Sharon L. Reed; Anne H. Rowley; Stanford T. Shulman; Helen Talbot; ...
    Persistent Identifiers
    Project: NIH | Genetic Influences &Gene ... (1R01HL069413-01), NIH | STRUCTURE AND FUNCTION OF... (1R01AI045798-01A2)

    Kawasaki disease (KD) is a self-limited, systemic vasculitis of children for which an infectious trigger is suspected. Recently, an association between KD and human coronavirus ( HCoV) - New Haven (NH) was reported, on the basis of polymerase chain reaction (PCR) with p...

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  • publication . Article . 2014
    Open Access English
    Authors:
    Ann R. Falsey; Janet E. McElhaney; Jiri Beran; Gerrit A van Essen; Xavier Duval; Meral Esen; Florence Galtier; Pierre Gervais; Shinn-Jang Hwang; Peter G. Kremsner; ...
    Persistent Identifiers
    Publisher: Oxford University Press
    Project: CIHR

    International audience; Background. Few studies have prospectively assessed viral etiologies of acute respiratory infections in community-based elderly individuals. We assessed viral respiratory pathogens in individuals ≥65 years with influenza-like illness (ILI).Method...

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  • publication . Article . 2017
    Open Access
    Authors:
    Anne W. Rimoin; Kai Lu; Matthew S. Bramble; Imke Steffen; Reena H. Doshi; Nicole A. Hoff; Patrick Mukadi; Bradly P. Nicholson; Vivian H. Alfonso; Gerrard Olinger; ...
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)
    Project: NIH | University of California ... (5D43TW009343-07), NIH | Serological prevalence of... (5R21AI107420-02)

    Duration of immunity against Ebola virus among survivors remains unclear. We assessed serological immune profiles and retention of Ebola virus neutralizing antibodies in 14 survivors of the 1976 Yambuku outbreak 40 years postinfection, providing the longest documentatio...

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  • publication . Article . 2004
    Open Access
    Authors:
    Leontine J. R. van Elden; Anton M. van Loon; Floris Van Alphen; Karin A. W. Hendriksen; Andy I. M. Hoepelman; Marian G. J. van Kraaij; Jan Jelrik Oosterheert; P. Schipper; Rob Schuurman; Monique Nijhuis;
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)

    During the past years, human coronaviruses (HCoVs) have been increasingly identified as pathogens associated with more-severe respiratory tract infection (RTI). Diagnostic tests for HCoVs are not frequently used in the routine setting. It is likely that, as a result, th...

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  • publication . Article . 2017
    Open Access
    Authors:
    Reina S. Sikkema; Elmoubasher Farag; Sayed Himatt; Adel K Ibrahim; Hamad Al-Romaihi; Salih A. Al-Marri; Mohamed Al-Thani; Ahmed M. El-Sayed; Mohammed Al-Hajri; Bart L. Haagmans; ...
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)
    Project: EC | COMPARE (643476), EC | PREPARE (602525)

    Abstract The transmission routes and risk factors for zoonotic Middle East respiratory syndrome coronavirus (MERS-CoV) infections are still unknown. We used the World Health Organization questionnaire for MERS-CoV case-control studies to assess risk factors for human ME...

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  • publication . Article . 2018
    Open Access English
    Authors:
    Patience K. Kiyuka; Charles N. Agoti; Patrick K. Munywoki; Regina Njeru; Anne Bett; James R. Otieno; Grieven P Otieno; Everlyn Kamau; Taane G. Clark; László van den Hoek; ...
    Persistent Identifiers
    Project: UKRI | Geographic genetic profil... (MR/M01360X/1), UKRI | The interactions between ... (MR/K000551/1), UKRI | Zika: Zika virus surveill... (MC_PC_15103), WT | Defining pathways of resp... (102975), UKRI | Understanding the transmi... (MR/N010469/1)

    Infections with human coronavirus NL63 are common and reinfections occur repeatedly throughout life. A subset of repeat infections show enhanced virus replication with no evidence of genotype switching, indicating that initial exposure is insufficient to elicit a protec...

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  • publication . Article . 2006
    Open Access English
    Authors:
    Luan-Yin Chang; Bor-Luen Chiang; Chuan-Liang Kao; Mei-Hwan Wu; Pei-Jer Chen; Ben Berkhout; Hui-Ching Yang; Li-Min Huang;
    Persistent Identifiers

    Abstract We investigated whether infection with a novel human coronavirus (HCoV), called “New Haven coronavirus” (HCoV-NH)—which is similar to and likely represents the same species as another novel HCoV, HCoV-NL63—is associated with Kawasaki disease (KD) in Taiwan. Fif...

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  • publication . Article . Other literature type . 2010
    Open Access
    Authors:
    Barry Rockx; Eric F. Donaldson; Matthew B. Frieman; Timothy P. Sheahan; Davide Corti; Antonio Lanzavecchia; Ralph S. Baric;
    Publisher: Oxford University Press (OUP)
    Project: NIH | SARS Reverse Genetics (5R01AI059136-03), NIH | Developing Vaccine Candid... (3P01AI059443-03S1)

    markdownabstractBackground. Severe acute respiratory syndrome (SARS) emerged as a human disease in 2002. Detailed phylogenetic analysis and epidemiologic studies have suggested that the SARS Coronavirus (SARS-CoV) originated from animals. The spike (S) glycoprotein has ...

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  • publication . Article . 2020
    Open Access English
    Authors:
    de Nooijer, Aline H; Grondman, Inge; Janssen, Nico A F; Netea, Mihai G; Willems, Loek; van de Veerdonk, Frank L; Giamarellos-Bourboulis, Evangelos J; Toonen, Erik J M; Joosten, Leo A B; Jaeger, Martin; ...
    Persistent Identifiers

    Abstract Background Excessive activation of immune responses in coronavirus disease 2019 (COVID-19) is considered to be related to disease severity, complications, and mortality rate. The complement system is an important component of innate immunity and can stimulate i...

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16 research outcomes, page 1 of 2