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12 research outcomes, page 1 of 2
  • publication . Article . Other literature type . 2011
    Open Access
    Authors:
    Annika Kühl; Markus Hoffmann; Marcel A. Müller; Vincent J. Munster; Kerstin Gnirß; Miriam Kiene; Theodros Solomon Tsegaye; Georg M. N. Behrens; Georg Herrler; Heinz Feldmann; ...
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)
    Project: EC | EMPERIE (223498)

    Infection with Ebola virus (EBOV) causes hemorrhagic fever in humans with high case-fatality rates. The EBOV-glycoprotein (EBOV-GP) facilitates viral entry and promotes viral release from human cells. African fruit bats are believed not to develop disease upon EBOV infe...

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  • publication . Article . 2017
    Open Access
    Authors:
    Anne W. Rimoin; Kai Lu; Matthew S. Bramble; Imke Steffen; Reena H. Doshi; Nicole A. Hoff; Patrick Mukadi; Bradly P. Nicholson; Vivian H. Alfonso; Gerrard Olinger; ...
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)
    Project: NIH | University of California ... (5D43TW009343-07), NIH | Serological prevalence of... (5R21AI107420-02)

    Duration of immunity against Ebola virus among survivors remains unclear. We assessed serological immune profiles and retention of Ebola virus neutralizing antibodies in 14 survivors of the 1976 Yambuku outbreak 40 years postinfection, providing the longest documentatio...

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  • publication . Article . 2017
    Open Access
    Authors:
    Reina S. Sikkema; Elmoubasher Farag; Sayed Himatt; Adel K Ibrahim; Hamad Al-Romaihi; Salih A. Al-Marri; Mohamed Al-Thani; Ahmed M. El-Sayed; Mohammed Al-Hajri; Bart L. Haagmans; ...
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)
    Project: EC | COMPARE (643476), EC | PREPARE (602525)

    Abstract The transmission routes and risk factors for zoonotic Middle East respiratory syndrome coronavirus (MERS-CoV) infections are still unknown. We used the World Health Organization questionnaire for MERS-CoV case-control studies to assess risk factors for human ME...

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  • publication . Article . 2020
    Open Access
    Authors:
    Toni Luise Meister; Yannick Brüggemann; Daniel Todt; Carina Conzelmann; Janis A Müller; Rüdiger Groß; Jan Münch; Adalbert Krawczyk; Jörg Steinmann; Jochen Steinmann; ...
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)
    Project: EC | Fight-nCoV (101003555)
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  • publication . Article . 2019
    Open Access
    Authors:
    Shi, Ting; Arnott, Andrew; Semogas, Indre; Falsey, Ann R; Openshaw, Peter; Wedzicha, Jadwiga A; Campbell, Harry; Nair, Harish; Nair, Harish; Campbell, Harry; ...
    Project: EC | RESCEU (116019), WT

    Abstract Acute respiratory tract infections (ARI) constitute a substantial disease burden in adults and elderly individuals. We aimed to identify all case-control studies investigating the potential role of respiratory viruses in the etiology of ARI in older adults aged...

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  • publication . Article . Other literature type . 2016
    Open Access
    Authors:
    Shweta Bansal; Gerardo Chowell; Lone Simonsen; Alessandro Vespignani; Cécile Viboud;
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)
    Project: EC | HistoricEpi (659437)

    We devote a special issue of the Journal of Infectious Diseases to review the recent advances of big data in strengthening disease surveillance, monitoring medical adverse events, informing transmission models, and tracking patient sentiments and mobility. We consider a...

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  • publication . Article . 2014
    Open Access English
    Authors:
    Stefanie Gierer; Marcel A. Müller; Adeline Heurich; Daniel Ritz; Benjamin L. Springstein; Christina B. Karsten; Alexander Schendzielorz; Kerstin Gnirß; Christian Drosten; Stefan Pöhlmann;
    Persistent Identifiers
    Publisher: Oxford University Press
    Project: EC | EMPERIE (223498)

    Abstract Middle East respiratory syndrome coronavirus (MERS-CoV) infection is associated with a high case-fatality rate, and the potential pandemic spread of the virus is a public health concern. The spike protein of MERS-CoV (MERS-S) facilitates viral entry into host c...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Nico A. F. Janssen; Inge Grondman; Aline H. de Nooijer; Collins K Boahen; Valerie A C M Koeken; Vasiliki Matzaraki; Vinod Kumar; Xuehui He; Matthijs Kox; Hans J. P. M. Koenen; ...
    Publisher: Oxford University Press (OUP)
    Project: EC | TRAIN-OLD (833247)

    <jats:title>Abstract</jats:title> <jats:p>The clinical spectrum of COVID-19 varies and the differences in host response characterizing this variation have not been fully elucidated. COVID-19 disease severity correlates with an excessive proinflammatory immune response a...

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  • publication . Article . 2014
    Open Access English
    Authors:
    Ziad A. Memish; Jaffar A. Al-Tawfiq; Hatem Q. Makhdoom; Abdullah M. Assiri; Raafat F. Alhakeem; Ali Albarrak; Sarah Alsubaie; Abdullah A Al-Rabeeah; Waleed H. Hajomar; Raheela Hussain; ...
    Persistent Identifiers
    Project: WT , EC | EMPERIE (223498), EC | ANTIGONE (278976)

    Abstract Background. Analysis of clinical samples from patients with new viral infections is critical to confirm the diagnosis, to specify the viral load, and to sequence data necessary for characterizing the viral kinetics, transmission, and evolution. We analyzed samp...

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  • publication . Article . 2020
    Open Access English
    Authors:
    Trieu, Mai-Chi; Bansal, Amit; Madsen, Anders; Zhou, Fan; Sævik, Marianne; Vahokoski, Juha; Brokstad, Karl Albert; Krammer, Florian; Tøndel, Camilla; Mohn, Kristin G I; ...
    Persistent Identifiers
    Publisher: Oxford University Press
    Project: EC | INCENTIVE (874866)

    Low numbers of SARS-CoV-2–seropositive HCW were found in Norway and 1.8% of HCW seroconverted with neutralizing antibodies. Seropositivity was higher than RT-PCR positivity in HCW with 36% asymptomatic, representing a risk of infection within the health care setting.

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12 research outcomes, page 1 of 2