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146 research outcomes, page 1 of 15
  • publication . Article . Preprint . 2020
    Open Access English
    Authors:
    Patrizio Vanella; Ugofilippo Basellini; Berit Lange;
    Persistent Identifiers
    Publisher: HAL CCSD
    Countries: France, Germany, France, France
    Project: EC | CORESMA (101003480)

    AbstractThe COVID-19 outbreak has called for renewed attention to the need for sound statistical analyses to monitor mortality patterns and trends over time. Excess mortality has been suggested as the most appropriate indicator to measure the overall burden of the pande...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Louis Jacob; Sven H. Loosen; Matthias Kalder; Tom Luedde; Christoph Roderburg; Karel Kostev;
    Persistent Identifiers
    Country: France
    Project: EC | PhaseControl (771083)

    28.2%). In addition, there was a significant decrease in almost all sex and age groups in April and May 2020 compared with the same period in 2019. Finally, the decrease in the number of new cancer diagnoses was particularly pronounced among cancers of the skin and the ...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Bernard Vanhove; Odile Duvaux; Juliette Rousse; Pierre-Joseph Royer; Gwénaëlle Evanno; Carine Ciron; Elsa Lheriteau; Laurent Vacher; Nadine Gervois; Romain Oger; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Country: France
    Project: EC | BRIGHT (962036)

    Abstract Heterologous polyclonal antibodies might represent an alternative to the use of convalescent plasma or monoclonal antibodies (mAbs) in coronavirus disease (COVID‐19) by targeting multiple antigen epitopes. However, heterologous antibodies trigger human natural ...

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  • publication . Article . Other literature type . 2020
    Open Access English
    Authors:
    Zhang, Q; Liu, Z; Moncada-Velez, M; Chen, J; Ogishi, M; Bigio, B; Yang, R; Arias, AA; Zhou, Q; Han, JE; ...
    Publisher: American Association for the Advancement of Science
    Countries: Belgium, France, Switzerland, Italy, France, Turkey, France, Belgium, Spain, Belgium ...
    Project: EC | EASI-Genomics (824110)

    COVID Human Genetic Effort Laurent Abel1, Alessandro Aiuti2, Saleh Al Muhsen3, Fahd Al-Mulla4, Mark S. Anderson5, Andrés Augusto Arias6, Hagit Baris Feldman7, Dusan Bogunovic8, Alexandre Bolze9, Anastasiia Bondarenko10, Ahmed A. Bousfiha11, Petter Brodin12, Yenan Bryces...

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  • publication . Article . 2019
    Open Access
    Authors:
    Sierżant, K.; Perruchot, M-H.; Merlot, E.; Le Floc’h, N.; Gondret, F.;
    Persistent Identifiers
    Publisher: Springer Science and Business Media LLC
    Country: France
    Project: EC | PROHEALTH (613574)

    AbstractBackgroundPoor hygiene of housing induces a systemic inflammatory response. Because inflammation and oxidative stress are processes that can sustain each other, the ways pigs are able to activate their antioxidant defenses are critical for production performance...

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  • publication . Article . 2010
    Open Access English
    Authors:
    Laura I. Levi; Nina F. Gnädig; Stéphanie Beaucourt; Malia J. McPherson; Bruno Baron; Jamie J. Arnold; Marco Vignuzzi;
    Publisher: Public Library of Science
    Country: France
    Project: EC | RNAVIRUSPOPDIVNVAX (242719), ANR | QuasispeciesVax (ANR-09-JCJC-0118), NIH | RNA DEPENDENT RNA POLYMER... (5R01AI045818-05)

    Author Summary RNA viruses have extreme mutation frequencies, due in large part to the erroneous nature of the viral RNA dependent RNA polymerases (RdRp) that replicate their genomes. Since RdRp lack proofreading and repair mechanisms, the use of base analogs as RNA mut...

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  • publication . Article . 2017
    Open Access English
    Authors:
    Mathilde Richard; Sascha Knauf; Philip Lawrence; Alison E. Mather; Vincent J. Munster; Marcel A. Müller; Derek J. Smith; Thijs Kuiken;
    Publisher: Elsevier BV
    Countries: United Kingdom, Germany, France, United Kingdom, France, France, Netherlands
    Project: EC | ANTIGONE (278976), EC | ZAPI (115760), UKRI | The devil we know? Using ... (BB/M014088/1)

    The pandemic potential of zoonotic pathogens lies in their ability to become efficiently transmissible amongst humans. Here, we focus on contact-transmitted pathogens and discuss the factors, at the pathogen, host and environmental levels that promote or hinder their hu...

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  • publication . Article . Other literature type . 2016
    Open Access English
    Authors:
    Li, Changqing; Debing, Yannick; Jankevicius, Gytis; Neyts, Johan; Ahel, Ivan; Coutard, Bruno; Canard, Bruno;
    Persistent Identifiers
    Publisher: HAL CCSD
    Countries: France, United Kingdom
    Project: EC | EUVIRNA (264286), EC | SILVER (260644)

    ABSTRACT ADP-ribosylation is a posttranslational protein modification in which ADP-ribose is transferred from NAD + to specific acceptors to regulate a wide variety of cellular processes. The macro domain is an ancient and highly evolutionarily conserved protein domain...

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  • publication . Other literature type . Article . 2016
    Open Access English
    Authors:
    Madelain, Vincent; Nguyen, Thi Huyen Tram; Olivo, Anaelle; de Lamballerie, Xavier; Guedj, Jérémie; Taburet, Anne-Marie; Mentré, France;
    Persistent Identifiers
    Publisher: HAL CCSD
    Country: France
    Project: EC | REACTION (666092), EC | EVIDENT (666100)

    International audience; The 2014-2015 outbreak of Ebola virus disease (EVD) is the largest epidemic to date in terms of number of cases, of death and affected areas. In October 2015, no antiviral agents had proven an antiviral efficacy in patients. However in September ...

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  • publication . Article . 2020
    Open Access English
    Authors:
    Eloi Marijon; Nicole Karam; Daniel Jost; David Perrot; Benoit Frattini; Clément Derkenne; Ardalan Sharifzadehgan; Victor Waldmann; Frankie Beganton; Kumar Narayanan; ...
    Publisher: HAL CCSD
    Country: France
    Project: EC | ESCAPE-NET (733381)

    Summary Background Although mortality due to COVID-19 is, for the most part, robustly tracked, its indirect effect at the population level through lockdown, lifestyle changes, and reorganisation of health-care systems has not been evaluated. We aimed to assess the inci...

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146 research outcomes, page 1 of 15