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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/

    Zbirka radova

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Repository of the Un...arrow_drop_down
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Repository of the Un...arrow_drop_down
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/

    Zbirka radova

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Repository of the Un...arrow_drop_down
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Repository of the Un...arrow_drop_down
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Arbanas, Goran; Roksandić, Sunčana;

    The COVID-19 pandemic has opened new questions in rendering of health care that need to be addressed. As the COVID-19 pandemic occurred during the period of respect for “human rights”, in this article the authors are comparing the provisions concerning health protection and restriction of the rights of two vulnerable categories, persons with mental disorders, and persons suspected of suffering from, or suffering from infectious diseases. Both vulnerable groups are categories of persons whose liberty may be restricted without their will in certain cases. The article points out certain vagueness of the Law on the Protection of the Population from Infectious Diseases regarding the (judicial) control of imposed security measures, especially in comparison with the Law on the Protection of Persons with Mental Disabilities. In the conclusion, the authors are providing some possible solutions to the observed ambiguities. The authors analyze the legal protection of these categories of persons in relation to the exercise of their right to health and in the context of Art. 16 of the Constitution of the Republic of Croatia. This Article enables the restriction of rights and freedoms in order to protect the freedoms and rights of other people, legal order, public morals and health, which must be proportionate to the nature of the need for restriction. Pandemija COVID-19 otvorila je neka nova pitanja u pružanju zdravstvene zaštite na koja je nužno odgovoriti u suočavanju s ovom pandemijom. Kako se pandemija COVID-19 javila u razdoblju poštivanja „ljudskih prava“, u ovom članku uspoređujemo odredbe koje se tiču zaštite zdravlja te ograničavanje prava dviju ranjivih kategorija, osoba s duševnim smetnjama i osoba za koje postoji sumnja da boluju ili boluju od zaraznih bolesti, budući da se radi o kategorijama osoba čija sloboda može biti ograničena bez njihove volje u određenim slučajevima. Članak ukazuje na nedorečenosti Zakona o zaštiti pučanstva od zaraznih bolesti vezano uz (sudsku) kontrolu izrečenih sigurnosnih mjera, poglavito u usporedbi sa Zakonom o zaštiti osoba s duševnim smetnjama. U zaključku navodimo možebitna rješenja uočenih nedorečenosti. Autori analiziraju pravnu zaštitu navedenih kategorija osoba u odnosu na ostvarivanje njihovog prava na zdravlje i u kontekstu čl. 16 Ustava RH koji omogućuje ograničavanje prava i sloboda da bi se zaštitila sloboda i prava drugih ljudi, pravni poredak, javni moral i zdravlje, što mora biti razmjerno naravi potrebe za ograničavanjem.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Repository of the Un...arrow_drop_down
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Repository of the Un...arrow_drop_down
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Zubović, Ines; Banac, Srđan;

    Aim: To present a series of cases of pediatric patients who have been tested positively to anti-SARS-CoV-2 IgG and who have developed multisystem inflammatory syndrome that occurred because of COVID19 infection. In its definition, it implies symptoms such as fever, signs affecting two or more organ systems, positive contact with the COVID19 virus while excluding other causes and describing the efficacy of applied immunosuppressive therapy. Case report: Four pediatric patients aged 18 months, 9, 10 and 15 years were referred to an emergency pediatric clinic because of the persistent fever and symptoms of various organ systems. In the case of four patients, three out of the four patients had vomiting, diarrhea, rash and conjunctivitis as their main symptoms, and in the case of the remaining patient, their symptoms were the impaired gait and weakened tendon reflexes of the legs. In all patients the laboratory findings confirmed acute inflammation, and due to elevated brain natriuretic peptide they underwent the cardiac processing. The ultrasound of the heart showed mitral regurgitation in two patients, and in one pericardial effusion. After the diagnoses — the multisystem inflammatory response, the therapy in the case of our patients was in line with the unofficial world 1 European guidelines. They were administered intravenously immunoglobulins 1 corticosteroids and fluid replacement as well as the vasoactive drugs. Given the fact, that in this way it is possible for the bacterial sepsis to present itself upon arrival — hemoculture broad-spectrum antibiotics were administered. All four patients have recovered and were released home. Conclusion: Timely detection and treatment of the multisystem inflammatory response also means a better outcome for the patient. Potential future research could focus on elucidating this condition and possible Ik long-term consequences, and thus prevent severe clinical images. Cilj: Prikazati seriju slučajeva anti-SARS-CoV-2 IgG pozitivnih pedijatrijskih pacijenata koji su razvili multisistemski upalni sindrom koji se javio kao posljedica bolesti COVID-19, a u svojoj definiciji objedinjuje povišenu tjelesnu temperaturu, znakove zahvaćanja dvaju ili više organskih sustava, pozitivan kontakt s koronavirusom i isključivanje drugih uzročnika, kao i opisati učinkovitost primijenjene imunosupresivne terapije. Prikaz slučaja: Četiri pedijatrijska pacijenta u dobi od 18 mjeseci, 9, 10 i 15 godina bila su upućena u hitnu pedijatrijsku ambulantu zbog perzistentnog febriliteta i simptoma različitih organskih sustava. Kod troje pacijenata glavni su simptomi bili povraćanje, proljev, osip i konjunktivitis, a u jednog se pacijenta isticao otežan hod i oslabljeni tetivni refleksi nogu. U svih pacijenata laboratorijski su nalazi potvrdili akutnu upalu, a zbog povišenog moždanog natriuretskog peptida učinjena je kardiološka obrada. Ultrazvuk srca je kod dvaju pacijenata pokazao mitralnu insuficijenciju, a kod jednog perikardijalni izljev. Nakon postavljene dijagnoze multisistemskog upalnog odgovora terapija je u slučaju naših pacijenata bila u skladu s neslužbenim svjetskim i europskim smjernicama. Primijenjeni su intravenski imunoglobulini i kortikosteroidi te nadoknada tekućine i vazoaktivni lijekovi. Budući da se na ovaj način može prezentirati bakterijska sepsa do dolaska hemokultura, primijenjeni su antibiotici širokog spektra. Sva su četiri pacijenta ozdravila te su puštena kući. Zaključak: Pravovremeno otkrivanje i liječenje multisistemskog upalnog odgovora ujedno znači i bolji ishod za pacijenta. Potencijalna buduća istraživanja mogla bi se usmjeriti na razjašnjavanje ovog stanja i mogućih dugoročnih posljedica, a na taj način i spriječiti teške kliničke slike.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Repository of the Un...arrow_drop_down
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Repository of the Un...arrow_drop_down
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Čivljak, Rok; Markotić, Alemka; Kuzman, Ilija;

    The current epidemic of a new coronavirus disease (COVID-19), caused by a novel coronavirus (2019-nCoV), recently officially named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has reopened the issue of the role and importance of coronaviruses in human pathology (1-5). This epidemic definitively confirms that this heretofore relatively harmless family of viruses, Coronaviridae, includes major pathogens of epidemic potential. The COVID-19 epidemic has clearly demonstrated the power of infectious diseases, which have been responsible for many devastating epidemics throughout history. The epidemiological potential of emerging infectious diseases, especially zoonoses, is affected by numerous environmental, epidemiological, social, and economic factors (6,7). Emerging zoonoses pose both epidemiological and clinical challenges to health care professionals. Since the 1960s, coronaviruses have caused a wide variety of human and animal diseases. In humans, they cause up to a third of all community-acquired upper respiratory tract infections, such as the common cold, pharyngitis, and otitis media. However, more severe forms of bronchiolitis, exacerbations of asthma, and pneumonia in children and adults have also been described, sometimes with fatal outcomes in infants, the elderly, and the immunocompromised. Some coronaviruses are associated with gastrointestinal disease in children. Sporadic infections of the central nervous system have also been reported, although the role of coronaviruses in infections outside the respiratory tract has not been completely clarified.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Repository of the Un...arrow_drop_down
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/

    Zbirka radova

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Repository of the Un...arrow_drop_down
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Repository of the Un...arrow_drop_down
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/

    Zbirka radova

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Repository of the Un...arrow_drop_down
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Repository of the Un...arrow_drop_down
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
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    Authors: Arbanas, Goran; Roksandić, Sunčana;

    The COVID-19 pandemic has opened new questions in rendering of health care that need to be addressed. As the COVID-19 pandemic occurred during the period of respect for “human rights”, in this article the authors are comparing the provisions concerning health protection and restriction of the rights of two vulnerable categories, persons with mental disorders, and persons suspected of suffering from, or suffering from infectious diseases. Both vulnerable groups are categories of persons whose liberty may be restricted without their will in certain cases. The article points out certain vagueness of the Law on the Protection of the Population from Infectious Diseases regarding the (judicial) control of imposed security measures, especially in comparison with the Law on the Protection of Persons with Mental Disabilities. In the conclusion, the authors are providing some possible solutions to the observed ambiguities. The authors analyze the legal protection of these categories of persons in relation to the exercise of their right to health and in the context of Art. 16 of the Constitution of the Republic of Croatia. This Article enables the restriction of rights and freedoms in order to protect the freedoms and rights of other people, legal order, public morals and health, which must be proportionate to the nature of the need for restriction. Pandemija COVID-19 otvorila je neka nova pitanja u pružanju zdravstvene zaštite na koja je nužno odgovoriti u suočavanju s ovom pandemijom. Kako se pandemija COVID-19 javila u razdoblju poštivanja „ljudskih prava“, u ovom članku uspoređujemo odredbe koje se tiču zaštite zdravlja te ograničavanje prava dviju ranjivih kategorija, osoba s duševnim smetnjama i osoba za koje postoji sumnja da boluju ili boluju od zaraznih bolesti, budući da se radi o kategorijama osoba čija sloboda može biti ograničena bez njihove volje u određenim slučajevima. Članak ukazuje na nedorečenosti Zakona o zaštiti pučanstva od zaraznih bolesti vezano uz (sudsku) kontrolu izrečenih sigurnosnih mjera, poglavito u usporedbi sa Zakonom o zaštiti osoba s duševnim smetnjama. U zaključku navodimo možebitna rješenja uočenih nedorečenosti. Autori analiziraju pravnu zaštitu navedenih kategorija osoba u odnosu na ostvarivanje njihovog prava na zdravlje i u kontekstu čl. 16 Ustava RH koji omogućuje ograničavanje prava i sloboda da bi se zaštitila sloboda i prava drugih ljudi, pravni poredak, javni moral i zdravlje, što mora biti razmjerno naravi potrebe za ograničavanjem.

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    Authors: Zubović, Ines; Banac, Srđan;

    Aim: To present a series of cases of pediatric patients who have been tested positively to anti-SARS-CoV-2 IgG and who have developed multisystem inflammatory syndrome that occurred because of COVID19 infection. In its definition, it implies symptoms such as fever, signs affecting two or more organ systems, positive contact with the COVID19 virus while excluding other causes and describing the efficacy of applied immunosuppressive therapy. Case report: Four pediatric patients aged 18 months, 9, 10 and 15 years were referred to an emergency pediatric clinic because of the persistent fever and symptoms of various organ systems. In the case of four patients, three out of the four patients had vomiting, diarrhea, rash and conjunctivitis as their main symptoms, and in the case of the remaining patient, their symptoms were the impaired gait and weakened tendon reflexes of the legs. In all patients the laboratory findings confirmed acute inflammation, and due to elevated brain natriuretic peptide they underwent the cardiac processing. The ultrasound of the heart showed mitral regurgitation in two patients, and in one pericardial effusion. After the diagnoses — the multisystem inflammatory response, the therapy in the case of our patients was in line with the unofficial world 1 European guidelines. They were administered intravenously immunoglobulins 1 corticosteroids and fluid replacement as well as the vasoactive drugs. Given the fact, that in this way it is possible for the bacterial sepsis to present itself upon arrival — hemoculture broad-spectrum antibiotics were administered. All four patients have recovered and were released home. Conclusion: Timely detection and treatment of the multisystem inflammatory response also means a better outcome for the patient. Potential future research could focus on elucidating this condition and possible Ik long-term consequences, and thus prevent severe clinical images. Cilj: Prikazati seriju slučajeva anti-SARS-CoV-2 IgG pozitivnih pedijatrijskih pacijenata koji su razvili multisistemski upalni sindrom koji se javio kao posljedica bolesti COVID-19, a u svojoj definiciji objedinjuje povišenu tjelesnu temperaturu, znakove zahvaćanja dvaju ili više organskih sustava, pozitivan kontakt s koronavirusom i isključivanje drugih uzročnika, kao i opisati učinkovitost primijenjene imunosupresivne terapije. Prikaz slučaja: Četiri pedijatrijska pacijenta u dobi od 18 mjeseci, 9, 10 i 15 godina bila su upućena u hitnu pedijatrijsku ambulantu zbog perzistentnog febriliteta i simptoma različitih organskih sustava. Kod troje pacijenata glavni su simptomi bili povraćanje, proljev, osip i konjunktivitis, a u jednog se pacijenta isticao otežan hod i oslabljeni tetivni refleksi nogu. U svih pacijenata laboratorijski su nalazi potvrdili akutnu upalu, a zbog povišenog moždanog natriuretskog peptida učinjena je kardiološka obrada. Ultrazvuk srca je kod dvaju pacijenata pokazao mitralnu insuficijenciju, a kod jednog perikardijalni izljev. Nakon postavljene dijagnoze multisistemskog upalnog odgovora terapija je u slučaju naših pacijenata bila u skladu s neslužbenim svjetskim i europskim smjernicama. Primijenjeni su intravenski imunoglobulini i kortikosteroidi te nadoknada tekućine i vazoaktivni lijekovi. Budući da se na ovaj način može prezentirati bakterijska sepsa do dolaska hemokultura, primijenjeni su antibiotici širokog spektra. Sva su četiri pacijenta ozdravila te su puštena kući. Zaključak: Pravovremeno otkrivanje i liječenje multisistemskog upalnog odgovora ujedno znači i bolji ishod za pacijenta. Potencijalna buduća istraživanja mogla bi se usmjeriti na razjašnjavanje ovog stanja i mogućih dugoročnih posljedica, a na taj način i spriječiti teške kliničke slike.

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    Authors: Čivljak, Rok; Markotić, Alemka; Kuzman, Ilija;

    The current epidemic of a new coronavirus disease (COVID-19), caused by a novel coronavirus (2019-nCoV), recently officially named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has reopened the issue of the role and importance of coronaviruses in human pathology (1-5). This epidemic definitively confirms that this heretofore relatively harmless family of viruses, Coronaviridae, includes major pathogens of epidemic potential. The COVID-19 epidemic has clearly demonstrated the power of infectious diseases, which have been responsible for many devastating epidemics throughout history. The epidemiological potential of emerging infectious diseases, especially zoonoses, is affected by numerous environmental, epidemiological, social, and economic factors (6,7). Emerging zoonoses pose both epidemiological and clinical challenges to health care professionals. Since the 1960s, coronaviruses have caused a wide variety of human and animal diseases. In humans, they cause up to a third of all community-acquired upper respiratory tract infections, such as the common cold, pharyngitis, and otitis media. However, more severe forms of bronchiolitis, exacerbations of asthma, and pneumonia in children and adults have also been described, sometimes with fatal outcomes in infants, the elderly, and the immunocompromised. Some coronaviruses are associated with gastrointestinal disease in children. Sporadic infections of the central nervous system have also been reported, although the role of coronaviruses in infections outside the respiratory tract has not been completely clarified.

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