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4 research outcomes, page 1 of 1
  • publication . Article . Other literature type . 2018
    Open Access English
    Authors:
    Mario Mauthe; Idil Orhon; Cecilia Rocchi; Xingdong Zhou; Morten Luhr; Kerst-Jan Hijlkema; Robert P. Coppes; Nikolai Engedal; Muriel Mari; Fulvio Reggiori;
    Country: Netherlands
    Project: EC | PRONKJEWAIL (713660), SNSF | ER-phagy mechanisms to ma... (CRSII3_154421)

    Macroautophagy/autophagy is a conserved transport pathway where targeted structures are sequestered by phagophores, which mature into autophagosomes, and then delivered into lysosomes for degradation. Autophagy is involved in the pathophysiology of numerous diseases and...

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  • publication . Article . 2017
    Open Access English
    Authors:
    Yingying Cong; Pauline Verlhac; Fulvio Reggiori;
    Publisher: MDPI AG
    Country: Netherlands
    Project: SNSF | ER-phagy mechanisms to ma... (CRSII3_154421), NWO | A three-dimensional look ... (2300175771), EC | PRONKJEWAIL (713660)

    Autophagy is a conserved intracellular catabolic pathway that allows cells to maintain homeostasis through the degradation of deleterious components via specialized double-membrane vesicles called autophagosomes. During the past decades, it has been revealed that numero...

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  • publication . Article . 2016
    Open Access English
    Authors:
    Mario Mauthe; Martijn A. Langereis; Jennifer Jung; Xingdong Zhou; Alex Jones; Wienand A. Omta; Sharon A. Tooze; Bjoern Stork; Søren R. Paludan; Tero Ahola; ...
    Country: Netherlands
    Project: EC | XABA (282333), NWO | A three-dimensional look ... (2300175771), AKA | Mechanisms in the formati... (265997), SNSF | ER-phagy mechanisms to ma... (CRSII3_154421), NWO | The role of autophagy in ... (2300175628), NWO | Viral strategies to evade... (2300180032), WT

    Autophagy is a catabolic process regulated by the orchestrated action of the autophagy-related (ATG) proteins. Recent work indicates that some of the ATG proteins also have autophagy-independent roles. Using an unbiased siRNA screen approach, we explored the extent of t...

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  • other research product . Other ORP type . 2017
    Open Access English
    Authors:
    Cong, Yingying; Verlhac, Pauline; Reggiori, Fulvio;
    Project: EC | PRONKJEWAIL (713660), NWO | A three-dimensional look ... (2300175771), SNSF | ER-phagy mechanisms to ma... (CRSII3_154421)

    Autophagy is a conserved intracellular catabolic pathway that allows cells to maintain homeostasis through the degradation of deleterious components via specialized double-membrane vesicles called autophagosomes. During the past decades, it has been revealed that numero...

4 research outcomes, page 1 of 1