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The following results are related to COVID-19. Are you interested to view more results? Visit OpenAIRE - Explore.
295 Research products, page 1 of 30

  • COVID-19
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  • Open Access
  • HAL - UPEC / UPEM

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  • Open Access English
    Authors: 
    Mathieu Bourgarel; Davies M. Pfukenyi; Vanina Boué; Loïc Talignani; Ngoni Chiweshe; Fodé Diop; Alexandre Caron; Gift Matope; Dorothée Missé; Florian Liegeois;
    Country: France
    Project: ANR | TIMTAMDEN (ANR-14-CE14-0029)

    Bats carry a great diversity of zoonotic viruses with a high-impact on human health and livestock. Since the emergence of new coronaviruses and paramyxoviruses in humans (e.g. Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and Nipah virus), numerous studies cl...

  • Open Access English
    Authors: 
    Ilies Benotmane; Timothée Bruel; Delphine Planas; Samira Fafi-Kremer; Olivier Schwartz; Sophie Caillard;
    Publisher: HAL CCSD
    Country: France

    AbstractIn immunocompetent subjects, the effectiveness of SARS-CoV-2 vaccines against the delta variant appears three- to five-fold lower than that observed against the alpha variant. Additionally, three doses of SARS-CoV-2 mRNA-based vaccines might be unable to elicit ...

  • Open Access English
    Authors: 
    Young-Jun Park; Kaitlyn D. LaCourse; Christian Cambillau; Frank DiMaio; Joseph D. Mougous; David Veesler;
    Publisher: Nature Publishing Group
    Country: France
    Project: NIH | Protein structure determi... (1R01GM123089-01)

    Type VI secretion systems (T6SSs) translocate effectors into target cells and are made of a contractile sheath and a tube docked onto a multi-protein transmembrane complex via a baseplate. Although some information is available about the mechanisms of tail contraction l...

  • Open Access English
    Authors: 
    Jérémy Dufloo; Ludivine Grzelak; Isabelle Staropoli; Yoann Madec; Laura Tondeur; François Anna; Stéphane Pelleau; Aurélie Wiedemann; Cyril Planchais; Julian Buchrieser; +10 more
    Publisher: HAL CCSD
    Country: France
    Project: EC | EVA-GLOBAL (871029)

    A large proportion of SARS-CoV-2 infected individuals remains asymptomatic. Little is known about the extent and quality of their antiviral humoral response. Here, we analyze antibody functions in 52 asymptomatic infected individuals, 119 mild and 21 hospitalized COVID-...

  • Open Access English
    Authors: 
    Fauroux, Brigitte; Khirani, Sonia; Amaddeo, Alessandro; MASSENAVETTE, Bruno; Bierme, Priscille; Taytard, Jessica; Stremler, Nathalie; Baravalle-Einaudi, Melisande; Mazenq, Julie; Ioan, Iulia; +56 more
    Publisher: HAL CCSD
    Country: France

    International audience; Bronchopulmonary infections are a major trigger of cardiac decompensation and are frequently associated with hospitalizations in patients with heart failure (HF). Adverse cardiac effects associated with respiratory infections, more specifically S...

  • Publication . Conference object . Preprint . Article . 2020
    Open Access English
    Authors: 
    Hadrien Titeux; Rachid Riad; Xuan-Nga Cao; Nicolas Hamilakis; Kris Madden; Alejandrina Cristia; Anne-Catherine Bachoud-Lévi; Emmanuel Dupoux;
    Publisher: HAL CCSD
    Country: France
    Project: ANR | ACLEW (ANR-16-DATA-0004), ANR | PRAIRIE (ANR-19-P3IA-0001), ANR | LangAge (ANR-17-CE28-0007), ANR | PSL (ANR-10-IDEX-0001), ANR | MechELex (ANR-14-CE30-0003), ANR | FrontCog (ANR-17-EURE-0017)

    International audience; We introduce Seshat, a new, simple and open-source software to efficiently manage annotations of speech corpora. The Seshat software allows users to easily customise and manage annotations of large audio corpora while ensuring compliance with the...

  • Open Access English
    Authors: 
    Robin Ohannessian; Tu Anh Duong; Anna Odone;
    Publisher: HAL CCSD
    Country: France

    International audience; On March 11, 2020, the World Health Organization declared the coronavirus disease 2019 (COVID-19) outbreak as a pandemic, with over 720,000 cases reported in more than 203 countries as of 31 March. The response strategy included early diagnosis, ...

  • Open Access English
    Authors: 
    Izza Nasrullah; Azeem Mehmood Butt; Shifa Tahir; Muhammad Idrees; Yigang Tong;
    Publisher: HAL CCSD
    Country: France

    Abstract Background The Marburg virus (MARV) has a negative-sense single-stranded RNA genome, belongs to the family Filoviridae, and is responsible for several outbreaks of highly fatal hemorrhagic fever. Codon usage patterns of viruses reflect a series of evolutionary ...

  • Open Access English
    Authors: 
    Lavillette, Dimitri; Barbouche, Rym; Yao, Yongxiu; Boson, Bertrand; Cosset, François-Loïc; Jones, Ian M; Fenouillet, Emmanuel;
    Publisher: HAL CCSD
    Country: France

    The capacity of the surface glycoproteins of enveloped viruses to mediate virus/cell binding and membrane fusion requires a proper thiol/disulfide balance. Chemical manipulation of their redox state using reducing agents or free sulfhydryl reagents affects virus/cell in...

  • Open Access English
    Authors: 
    Changqing Li; Jaime Guillén; Nadia Rabah; Alexandre Blanjoie; Françoise Debart; Jean-Jacques Vasseur; Bruno Canard; Etienne Decroly; Bruno Coutard;
    Publisher: HAL CCSD
    Country: France

    ABSTRACT Alphaviruses are known to possess a unique viral mRNA capping mechanism involving the viral nonstructural protein nsP1. This enzyme harbors methyltransferase (MTase) and nsP1 guanylylation (GT) activities catalyzing the transfer of the methyl group from S -ade...