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The following results are related to COVID-19. Are you interested to view more results? Visit OpenAIRE - Explore.
9,134 Research products, page 1 of 914

  • COVID-19
  • Research data
  • Other research products
  • 2018-2022
  • Other ORP type

  • German
    Klink, Philipp; Sardesai, Saskia; Gehring, Janine; Görtz, Michael Dominik;
    Publisher: Fraunhofer IML
    Country: Germany

    Für die heutige Weltwirtschaft ist eine globale Arbeitsteilung charakteristisch. Dabei hängt die Produktion von globalen Supply Chains ab, bei der die Logistik das Rückgrat dieser verteilten Wertschöpfung darstellt. Aufgrund der COVID-19-Pandemie kommt es jedoch zu erforderlichen Lock-Downs in den einzelnen Ländern. Durch die zeitversetzten Stillstände der Wirtschaft gerät die global abhängige Produktion ins Ungleichgewicht. Vor diesem Hintergrund ist das Wissen über die Situation der Lieferanten für die Unternehmen von herausragender Relevanz. Die Situation erfordert einen Einblick, in welcher Art und Weise ihre Supply Chains durch die Pandemie betroffen werden und wie ein Wiederanlauf der Produktion nach einem Lock-Down erfolgreich aufzubauen ist. Nur so können zusätzliche wirtschaftliche Verluste vermieden werden. Es werden die Herausforderungen der Pandemie aufgezeigt und entsprechende Handlungsempfehlungen für den Wiederanlauf gegeben. Als unterstützendes Tool für relevante, aber kurzfristigen Entscheidungen stellt eine Simulation eine geeignete Möglichkeit zur realitätsnahen Abbildung der Supply Chain und die Auswirkungen bei Änderungen in der Supply Chain dar. Anhand einzelner Szenarien im Kontext der Pandemie werden resultierende Implikationen unter Einbeziehung von zeitabhängigen Wechselwirkungen für die Bewertung und Planung von Wiederanlauf-Szenarien erläutert. Dieses Whitepaper entstand im Rahmen eines mit Eigenmitteln der Fraunhofer Gesellschaft geförderten Forschungsprojekts als Beitrag zur Überwindung der wirtschaftlichen Auswirkungen der COVID-19-Pandemie.

  • Open Access English
    Mamelund, Svenn-Erik; Dimka, Jessica;
    Publisher: Routledge

    Despite common perceptions to the contrary, pandemic diseases do not affect populations indiscriminately. In this paper, we review literature produced by demographers, historians, epidemiologists, and other researchers on disparities during the 1918–20 influenza pandemic and the Covid-19 pandemic. Evidence from these studies demonstrates that lower socio-economic status and minority/stigmatized race or ethnicity are associated with higher morbidity and mortality. However, such research often lacks theoretical frameworks or appropriate data to explain the mechanisms underlying these disparities fully. We suggest using a framework that considers proximal and distal factors contributing to differential exposure, susceptibility, and consequences as one way to move this research forward. Further, current pandemic preparedness plans emphasize medically defined risk groups and epidemiological approaches. Therefore, we conclude by arguing in favour of a transdisciplinary paradigm that recognizes socially defined risk groups, includes input from the social sciences and humanities and other diverse perspectives, and contributes to the reduction of health disparities before a pandemic hits.

  • Open Access English
    Banco de España;
    Publisher: Banco de España
    Country: Spain
  • Open Access English
    Kinsella, Cormac M.; Santos, Pauline Dianne; Postigo-Hidalgo, Ignacio; Folgueiras-González, Alba; Passchier, Tim Casper; Szillat, Kevin P.; Akello, Joyce Odeke; Álvarez-Rodríguez, Beatriz; Martí-Carreras, Joan;

    The first cluster of patients suffering from coronavirus disease 2019 (COVID-19) was identified on December 21, 2019, and as of July 29, 2020, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections have been linked with 664,333 deaths and number at least 16,932,996 worldwide. Unprecedented in global societal impact, the COVID-19 pandemic has tested local, national, and international preparedness for viral outbreaks to the limits. Just as it will be vital to identify missed opportunities and improve contingency planning for future outbreaks, we must also highlight key successes and build on them. Concomitant to the emergence of a novel viral disease, there is a 'research and development gap' that poses a threat to the overall pace and quality of outbreak response during its most crucial early phase. Here, we outline key components of an adequate research response to novel viral outbreaks using the example of SARS-CoV-2. We highlight the exceptional recent progress made in fundamental science, resulting in the fastest scientific response to a major infectious disease outbreak or pandemic. We underline the vital role of the international research community, from the implementation of diagnostics and contact tracing procedures to the collective search for vaccines and antiviral therapies, sustained by unique information sharing efforts.

  • Open Access Portuguese
    Carneiro, António Vaz; Neto, Susana;
    Publisher: ISBE
    Country: Portugal

    O objectivo da Newsletter do Instituto de Saúde Baseado na Evidência (ISBE) é a disponibilização de informação sobre áreas relevantes para a prática clínica, baseada na melhor evidência científica. São localizados estudos relevantes e de alta qualidade, criticamente avaliados pela sua validade, importância dos resultados e aplicabilidade prática e resumidos numa óptica de suporte à decisão clínica. É dada prioridade aos estudos de causalidade – revisões sistemáticas, ensaios clínicos, estudos de coorte prospectivos/retrospectivos, estudos seccionais cruzados e caso‐controlo – incluindo‐se ainda, quando justificado, estudos qualitativos considerados de elevada qualidade metodológica e importância clínica.

  • Other research product . Other ORP type . 2021
    Open Access English
    Kooman, Jeroen P.; van der Sande, Frank M.;

    The COVID-19 pandemic has greatly affected nephrology. Firstly, dialysis patients appear to be at increased risk for infection due to viral transmission next to an enhanced risk for mortality as compared to the general population, even in the face of an often apparently mild clinical presentation. Derangements in the innate and adaptive immune systems may be responsible for a reduced antiviral response, whereas chronic activation of the innate immune system and endothelial dysfunction provide a background for a more severe course. The presence of severe comorbidity, older age, and a reduction of organ reserve may lead to a rapid deterioration of the clinical situation of the patients in case of severe infection. Secondly, patients with COVID-19 are at increased risk of acute kidney injury (AKI), which is related to the severity of the clinical disease. The presence of AKI, and especially the need for renal replacement therapy (RRT), is associated with an increased risk of mortality. AKI in COVID-19 has a multifactorial origin, in which direct viral invasion of kidney cells, activation of the renin-angiotensin aldosterone system, a hyperinflammatory response, hypercoagulability, and nonspecific factors such as hypotension and hypoxemia may be involved. Apart from logistic challenges and the need for strict hygiene within units, treatment of patients with ESRD and COVID-19 is not different from that of the general population. Extracorporeal treatment of patients with AKI with RRT can be complicated by frequent filter clotting due to the hypercoagulable state, for which regional citrate coagulation provides a reasonable solution. Also, acute peritoneal dialysis may be a reasonable option in these patients. Whether adjuncts to extracorporeal therapies, such as hemoadsorption, provide additional benefits in the case of severely ill COVID-19 patients needs to be addressed in controlled studies.

  • Open Access
    Direcció de Serveis de Comunicació Digital; Gerència de Recursos; Goroka (Firma); Guerrero, Laura;
    Publisher: Ajuntament de Barcelona
    Country: Spain

    El Departament de Salut i l’Ajuntament de Barcelona van posar en marxa els cribratges massius al Raval Nord de la ciutat. L’objectiu de l’actuació era detectar el màxim de casos asimptomàtics possibles, tallar cadenes de transmissió, aïllar contactes i limitar l’expansió del virus de la Covid-19. L’equip de veïnatge del Districte de Ciutat Vella va realitzar una campanya de difusió amb les comunitats culturals d’origen divers. La consellera de Salut, Alba Vergés i l’alcaldessa de Barcelona, Ada Colau, van destacar la importància de la realització de PCR’s. Imatges del 15 de setembre de 2020.

  • English
    Donadelli, Flavia;
    Publisher: London School of Economics and Political Science
    Country: United Kingdom

    An underlying assumption of modern political states is that they are rational systems that ‘follow the science’ to achieve optimal outcomes for their citizens. Whilst COVID-19 continues to foreground the strengths and weaknesses of different national scientific advice systems, Flavia Donadelli draws on evidence from Brazilian policymaking to argue that evidence informed policymaking is a far more ephemeral process and heavily dependent on institutional and political contexts for it to operate effectively.

  • Restricted
    Bolaños Solà, Marc; Verdaguer, Eric; Radeva, Petia;

    Requeriments tècnics: Ordinador que disposi de GPU Nvidia i Llibreries docker i docker-compose instalades al sistema. L'accés al manual i al codi no estarà disponible fins la fi de la data d'embargament. Si esteu interessats a accedir-hi, contacteu amb LogMask és un projecte basat en Intel·ligència Artificial (IA), Deep Learning i Big Data per a anàlisi per computació d'imatges en temps real. L'objectiu és saber si les persones porten (o no) posada una màscara protectora / preventiva a la cara (variants i / o alternatives) segons obligatorietat d'ús en aquest context de l'COVID-19. LogMask utilitza els últims avenços de la Intel·ligència Artificial, en particular l'Aprenentatge profund (Deep Learning) que permet avui en dia tenir: cotxes autònoms pel carrer, diagnosticar millor que els experts càncer en imatges mèdiques, etc. Projecte: UBTT0404