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9,120 research outcomes, page 1 of 912
  • research data . 2024
    English
    Authors:
    GRINZATO, Alessandro; Eaazhisai KANDIAH;
    Persistent Identifiers
    Publisher: European Synchrotron Radiation Facility

    The current COVID pandemic illustrates the potential of new emerging viruses and the necessity to explore the antiviral therapeutics. SARS-CoV2 nsp12 polymerase is a crucial drug target as it plays a key role in viral replication machinery. nsp12 performs the RNA depend...

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  • research data . 2024
    English
    Authors:
    WITTIG, Nina Kølln; KARPOV, Dmitry; PACUREANU, Alexandra JOITA;
    Persistent Identifiers
    Publisher: European Synchrotron Radiation Facility

    COVID-19 affects multiple vital organs and leads to drastic changes in tissue architecture not only in the lung but also in the heart. The understanding of these alterations is currently very limited and no high resolution 3D data is available. We propose to investigate...

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  • research data . 2024
    English
    Authors:
    PROUX, Olivier; NOBILI, Germano; PETROSINO, Maria;
    Persistent Identifiers
    Publisher: European Synchrotron Radiation Facility

    A promising way to develop therapeutic strategies against SARS-CoV-2 is to modulate the interactions of proteins coded in the viral genome with proteins expressed by the host organism. Within this framework, possible targets are the SARS-CoV-2 orf7a and orf8 non-structu...

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  • research data . 2024
    English
    Authors:
    MOURET, Stéphane; ADAM, Jean Francois; BRUN, Emmanuel; VILLANOVA, Julie;
    Publisher: European Synchrotron Radiation Facility

    Concomitantly to the first pandemic wave of Covid19, an unexpected high number of chilblains cases of the toes have been reported, without a clear demonstrated relationship between both phenomena. Histological studies are limited to 2D at a given resolution, whilst, tha...

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  • research data . 2023
    English
    Authors:
    FAVERO, Elena DEL; RICCI, Caterina; SZTUCKI, Michael; Narayanan THEYENCHERI;
    Persistent Identifiers
    Publisher: European Synchrotron Radiation Facility

    The aim of this project is to design and prototype hyaluronic acid sodium salt (HA)-dexamethasone nanoparticles for a synergic treatment of patients on ventilators in intensive care units, as in serious cases of COVID-19. The final goal is the development of a new promi...

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  • other research product . Other ORP type . 2022
    Open Access English
    Authors:
    Chen, Ziyue; Huang, Lizhen;
    Publisher: IGI Global

    Digital twins provide a solution for information-sharing between enterprises, thereby alleviating uncertainties in the supply chain. In light of the public crisis caused by COVID-19, the authors suggest a signal game model for a two-stage supply chain with two suppliers...

  • research data . 2021
    Open Access English
    Authors:
    Hursitoglu, Mehmet; Isiksacan, Nilgun; Erismis, Betul; Karandere, Faruk; Kural, Alev; Kumbasar, A Baki; Yasar, Kadriye Kart;
    Publisher: Zenodo

    This is the raw data of a study comparing in vitro cytokine , oxidative stres, and nasopharyngeal microbiota in early stage and recovery stage of COVID-19 patients with healthy controls. The published journal is Cytokine (https://doi.org/10.1016/j.cyto.2021.155757).

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  • other research product . Other ORP type . Collection . 2021
    Open Access English
    Authors:
    Boekel, L.; Hooijberg, F.; Vogelzang, E. H.; Klarenbeek, P. L.; Bos, W. H.; Tas, S. W.; Wolbink, G. J.;

    Abstract Clinical research projects often use traditional methods in which data collection and signing informed consent forms rely on patients’ visits to the research institutes. However, during challenging times when the medical community is in dire need of information...

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  • other research product . Other literature type . 2021
    Restricted English
    Authors:
    Perez-Invernon, Francisco Javier; Huntrieser, Heidi; Gordillo-Vazquez, Francisco J.; Soler, S.;
  • research data . 2021
    Open Access English
    Authors:
    González-Losada, Cristobal; González-Lodeiro, Luis Gabriel; Beato Canfux, Abraham Ismael; Fernández, Julio Raúl; Camacho, Hamlet; Vázquez-Blomquist, Diana; Guillén-Nieto, Gerardo Enrique;
    Publisher: Zenodo

    Abstract Background: The detection of SARS-CoV-2 genetic material from nasopharyngeal swab samples by RT-PCR is the most specific and sensitive way to test suspected cases. However, factors such as the sampling process, type of hyssop used, and the anatomical area from ...

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9,120 research outcomes, page 1 of 912