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The following results are related to COVID-19. Are you interested to view more results? Visit OpenAIRE - Explore.
228 Research products, page 1 of 23

  • COVID-19
  • Open Access
  • English
  • HAL - UPEC / UPEM
  • COVID-19

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  • Open Access English
    Authors: 
    Young-Jun Park; Kaitlyn D. LaCourse; Christian Cambillau; Frank DiMaio; Joseph D. Mougous; David Veesler;
    Publisher: Nature Portfolio
    Country: France
    Project: NIH | Protein structure determi... (1R01GM123089-01)

    Type VI secretion systems (T6SSs) translocate effectors into target cells and are made of a contractile sheath and a tube docked onto a multi-protein transmembrane complex via a baseplate. Although some information is available about the mechanisms of tail contraction l...

  • Open Access English
    Authors: 
    Lavillette, Dimitri; Barbouche, Rym; Yao, Yongxiu; Boson, Bertrand; François-Loïc, Cosset; Jones, Ian M; Fenouillet, Emmanuel;
    Country: France

    The capacity of the surface glycoproteins of enveloped viruses to mediate virus/cell binding and membrane fusion requires a proper thiol/disulfide balance. Chemical manipulation of their redox state using reducing agents or free sulfhydryl reagents affects virus/cell in...

  • Publication . Conference object . Preprint . Article . 2020
    Open Access English
    Authors: 
    Titeux, Hadrien; Riad, Rachid; Cao, Xuan-Nga; Hamilakis, Nicolas; Madden, Kris; Cristia, Alejandrina; Bachoud-Lévi, Anne-Catherine; Dupoux, Emmanuel;
    Publisher: HAL CCSD
    Country: France
    Project: ANR | MechELex (ANR-14-CE30-0003), ANR | FrontCog (ANR-17-EURE-0017), ANR | PSL (ANR-10-IDEX-0001), ANR | PRAIRIE (ANR-19-P3IA-0001), ANR | LangAge (ANR-17-CE28-0007), ANR | ACLEW (ANR-16-DATA-0004)

    International audience; We introduce Seshat, a new, simple and open-source software to efficiently manage annotations of speech corpora. The Seshat software allows users to easily customise and manage annotations of large audio corpora while ensuring compliance with the...

  • Open Access English
    Authors: 
    Fauroux, Brigitte; Khirani, Sonia; Amaddeo, Alessandro; MASSENAVETTE, Bruno; Bierme, Priscille; Taytard, Jessica; Stremler, Nathalie; Baravalle-Einaudi, Melisande; Mazenq, Julie; Ioan, Iulia; +56 more
    Publisher: HAL CCSD
    Country: France

    International audience; Bronchopulmonary infections are a major trigger of cardiac decompensation and are frequently associated with hospitalizations in patients with heart failure (HF). Adverse cardiac effects associated with respiratory infections, more specifically S...

  • Open Access English
    Authors: 
    M. Fieux; Antoine Gavoille; Fabien Subtil; Sophie Bartier; S. Tringali;
    Publisher: HAL CCSD
    Country: France

    Abstract Background The ongoing COVID-19 pandemic has disrupted the surgical training of residents. There is a real concern that trainees will not be able to meet their training requirements. Low-fidelity surgical simulation appears to be an alternative for surgical tra...

  • Open Access English
    Authors: 
    Jérémy Dufloo; Ludivine Grzelak; Isabelle Staropoli; Yoann Madec; Laura Tondeur; François Anna; Stéphane Pelleau; Aurélie Wiedemann; Cyril Planchais; Julian Buchrieser; +10 more
    Publisher: HAL CCSD
    Country: France
    Project: EC | EVA-GLOBAL (871029)

    A large proportion of SARS-CoV-2 infected individuals remains asymptomatic. Little is known about the extent and quality of their antiviral humoral response. Here, we analyze antibody functions in 52 asymptomatic infected individuals, 119 mild and 21 hospitalized COVID-...

  • Open Access English
    Authors: 
    Planchais, Cyril; Fernández, Ignacio; Bruel, Timothée; de Melo, Guilherme,; Prot, Matthieu; Beretta, Maxime; Guardado-Calvo, Pablo; Dufloo, Jérémy; Molinos-Albert, Luis,; Backovic, Marija; +122 more
    Publisher: HAL CCSD
    Country: France
    Project: EC | RECoVER (101003589)

    International audience; Memory B-cell and antibody responses to the SARS-CoV-2 spike protein contribute to long-term immune protection against severe COVID-19, which can also be prevented by antibody-based interventions. Here, wide SARS-CoV-2 immunoprofiling in Wuhan CO...

  • Open Access English
    Authors: 
    Izza Nasrullah; Azeem Mehmood Butt; Shifa Tahir; Muhammad Idrees; Yigang Tong;
    Publisher: HAL CCSD
    Country: France

    Abstract Background The Marburg virus (MARV) has a negative-sense single-stranded RNA genome, belongs to the family Filoviridae, and is responsible for several outbreaks of highly fatal hemorrhagic fever. Codon usage patterns of viruses reflect a series of evolutionary ...

  • Open Access English
    Authors: 
    Changqing Li; Jaime Guillén; Nadia Rabah; Alexandre Blanjoie; Françoise Debart; Jean-Jacques Vasseur; Bruno Canard; Etienne Decroly; Bruno Coutard;
    Publisher: American Society for Microbiology
    Country: France

    ABSTRACT Alphaviruses are known to possess a unique viral mRNA capping mechanism involving the viral nonstructural protein nsP1. This enzyme harbors methyltransferase (MTase) and nsP1 guanylylation (GT) activities catalyzing the transfer of the methyl group from S -ade...

  • Open Access English
    Authors: 
    Peter Czuppon; Emmanuel Schertzer; François Blanquart; Florence Débarre;
    Country: France
    Project: EC | PolyPath (844369), ANR | TheoGeneDrive (ANR-19-CE45-0009)

    Emerging epidemics and local infection clusters are initially prone to stochastic effects that can substantially impact the epidemic trajectory. While numerous studies are devoted to the deterministic regime of an established epidemic, mathematical descriptions of the i...