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156 research outcomes, page 1 of 16
  • publication . Preprint . Article . Other literature type . 2020
    Open Access English
    Authors:
    Franziska Hufsky; Kevin Lamkiewicz; Alexandre Almeida; Abdel Aouacheria; Cecilia N. Arighi; Alex Bateman; Jan Baumbach; Niko Beerenwinkel; Christian Brandt; Marco Cacciabue; ...
    Publisher: HAL CCSD
    Countries: France, Belgium, Germany, Denmark, Belgium, France, Argentina, Switzerland, France
    Project: UKRI | Rfam: The community resou... (BB/S020462/1), EC | EpiPose (101003688), EC | REPO-TRIAL (777111), WT | University of Edinburgh -... (203783), UKRI | Bilateral NSF/BIO-BBSRC:A... (BB/N018354/1), NIH | UniProt supporting an int... (3U24HG007822-05S1), UKRI | Capacity building for bio... (BB/P027849/1), EC | FeatureCloud (826078)

    SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is a novel virus of the family Coronaviridae. The virus causes the infectious disease COVID-19. The biology of coronaviruses has been studied for many years. However, bioinformatics tools designed explicitly f...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Michael Ceulemans; Veerle Foulon; Elin Ngo; Alice Panchaud; Ursula Winterfeld; Léo Pomar; Valentine Lambelet; Brian Cleary; Fergal O'Shaughnessy; Anneke Passier; ...
    Countries: Belgium, Switzerland
    Project: EC | DrugsInPregnancy (639377)

    INTRODUCTION: Evidence on perinatal mental health during the coronavirus disease 2019 (COVID-19) pandemic and its potential determinants is limited. Therefore, this multinational study aimed to assess the mental health status of pregnant and breastfeeding women during t...

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  • publication . Article . 2020
    Open Access English
    Authors:
    Gervasoni, Silvia; Vistoli, Giulio; Talarico, Carmine; Manelfi, Candida; Beccari, Andrea R.; Studer, Gabriel; Tauriello, Gerardo; Waterhouse, Andrew Mark; Schwede, Torsten; Pedretti, Alessandro;
    Persistent Identifiers
    Countries: Switzerland, Italy
    Project: EC | EXSCALATE4CoV (101003551)

    and (4) Conclusions: Even though the presented strategy should require more extended validations, this proved successful in precisely characterizing a set of SARS-CoV-2 druggable binding pockets including both orthosteric and allosteric sites, which are clearly amenable...

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  • publication . Other literature type . Article . 2020
    Open Access English
    Authors:
    Lynn Rochester; Claudia Mazzà; Arne Mueller; Brian Caulfield; M. McCarthy; Clemens Becker; Ram R. Miller; Paolo Piraino; Marco Viceconti; Wilhelmus P. Dartee; ...
    Persistent Identifiers
    Publisher: Karger Publishers
    Countries: Italy, Norway, United Kingdom
    Project: EC | MOBILISE-D (820820)

    Abstract Health care has had to adapt rapidly to COVID-19, and this in turn has highlighted a pressing need for tools to facilitate remote visits and monitoring. Digital health technology, including body-worn devices, offers a solution using digital outcomes to measure ...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Karl Blanchet; Grégoire Mallard; Erica Moret; Jin Sun;
    Persistent Identifiers
    Project: EC | PROSANCT (716216)

    AbstractCOVAX, the global initiative on COVID-19 vaccines, has set the target of achieving a COVID-19 vaccination coverage of up to 30% of the population of 135 countries in 2 years. Here, we argue that COVAX should anticipate important and unforeseen challenges with re...

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  • publication . Article . 2018
    Open Access English
    Authors:
    García-Nicolás, Obdulio; V'kovski, Philip; Vielle, Nathalie J.; Ebert, Nadine; Züst, Roland; Portmann, Jasmine; Stalder, Hanspeter; Gaschen, Véronique; Vieyres, Gabrielle; Stoffel, Michael; ...
    Persistent Identifiers
    Publisher: American Society for Microbiology
    Country: Germany
    Project: EC | ZIKAlliance (734548), SNSF | Host innate immune respon... (310030_173085), EC | COV RESTRIC (748627), SNSF | Zoonotic transmission of ... (320030E-165076), EC | PREDEMICS (278433)

    ABSTRACT The virus family Flaviviridae encompasses several viruses, including (re)emerging viruses which cause widespread morbidity and mortality throughout the world. Members of this virus family are positive-strand RNA viruses and replicate their genome in close assoc...

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  • publication . Article . 2016
    Open Access English
    Authors:
    Melanie Eck; Margarita García Durán; Meret E. Ricklin; Samira Locher; Javier Sarraseca; María José Morillo Rodríguez; Kenneth C. McCullough; Artur Summerfield; Gert Zimmer; Nicolas Ruggli;
    Persistent Identifiers
    Publisher: BioMed Central
    Countries: Switzerland, France
    Project: EC | PORRSCON (245141)

    International audience; AbstractPorcine reproductive and respiratory syndrome virus (PRRSV) is the causative agent of one of the most devastating and economically significant viral disease of pigs worldwide. The vaccines currently available on the market elicit only lim...

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  • publication . Preprint . 2021
    Open Access English
    Authors:
    Alberto Hernando; David Mateo; Bayer J; Barrios I;
    Persistent Identifiers
    Project: EC | DEMOGRAPHICA (872249)

    AbstractTotal and perimetral lockdowns were the strongest nonpharmaceutical interventions to fight against Covid-19, as well as the with the strongest socioeconomic collateral effects. Lacking a metric to predict the effect of lockdowns in the spreading of COVID-19, aut...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Imke H Bartelink; Pierre M Bet; Nicolas Widmer; Monia Guidi; Erik Duijvelaar; Bram Grob; Richard Honeywell; Amanda Evelo; Ivo P E Tielbeek; Sue D Snape; ...
    Persistent Identifiers
    Country: Netherlands
    Project: EC | Impentri (101005142)

    This study aimed to determine whether published pharmacokinetic (PK) models can adequately predict the PK profile of imatinib in a new indication, such as coronavirus disease 2019 (COVID-19). Total (bound + unbound) and unbound imatinib plasma concentrations obtained fr...

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  • publication . Article . 2021
    Embargo English
    Authors:
    L Cash-Gibson; JM Pericàs; C Spiertz; E van de Ketterij; E Molero; F Patalano; D Kalra; A Ussi; A Van Dessel; J Genescà;
    Persistent Identifiers
    Project: EC | EU-PEARL (853966)

    Abstract Issue Recently, innovative clinical trial designs have been proposed, which have the potential to revolutionize clinical research. Whereas classical trials mostly evaluate only one investigational drug, platform trials embed various trials under a shared maste...

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156 research outcomes, page 1 of 16