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COVID-19 European Commission CH English

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COVID-19 European Commission CH English

The following results are related to COVID-19. Are you interested to view more results? Visit OpenAIRE - Explore.
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156 research outcomes, page 1 of 16
  • publication . Preprint . Article . Other literature type . 2020
    Computational strategies to combat COVID-19: useful tools to accelerate SARS-CoV-2 and coronavirus research
    Open Access English
    Authors:
    Franziska Hufsky; Kevin Lamkiewicz; Alexandre Almeida; Abdel Aouacheria; Cecilia N. Arighi; Alex Bateman; Jan Baumbach; Niko Beerenwinkel; Christian Brandt; Marco Cacciabue; ...
    Persistent Identifiers

    doi: 10.17169/refubium-31299 , 10.20944/preprints202005.0376.v1 , 10.3929/ethz-b-000464448 , 10.1093/bib/bbaa232

    handle: 10033/622607 , 11336/128424 , 20.500.11850/464448 , 21.11116/0000-0007-EFDF-2 , 21.11116/0000-0007-EFE0-F , 21.11116/0000-0007-2E50-C

    pmc: PMC7665365

    pmid: 33147627

    Publisher: HAL CCSD
    Countries: France, Belgium, Germany, Denmark, Belgium, France, Argentina, Switzerland, France
    Project: UKRI | Rfam: The community resou... (BB/S020462/1), EC | EpiPose (101003688), EC | REPO-TRIAL (777111), WT | University of Edinburgh -... (203783), UKRI | Bilateral NSF/BIO-BBSRC:A... (BB/N018354/1), NIH | UniProt supporting an int... (3U24HG007822-05S1), UKRI | Capacity building for bio... (BB/P027849/1), EC | FeatureCloud (826078)

    SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is a novel virus of the family Coronaviridae. The virus causes the infectious disease COVID-19. The biology of coronaviruses has been studied for many years. However, bioinformatics tools designed explicitly f...

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  • publication . Article . 2021
    Mental health status of pregnant and breastfeeding women during the COVID‐19 pandemic—A multinational cross‐sectional study
    Open Access English
    Authors:
    Michael Ceulemans; Veerle Foulon; Elin Ngo; Alice Panchaud; Ursula Winterfeld; Léo Pomar; Valentine Lambelet; Brian Cleary; Fergal O'Shaughnessy; Anneke Passier; ...
    Persistent Identifiers

    doi: 10.48350/154669 , 10.1111/aogs.14092

    pmc: PMC8014496

    pmid: 33475148

    Countries: Belgium, Switzerland
    Project: EC | DrugsInPregnancy (639377)

    INTRODUCTION: Evidence on perinatal mental health during the coronavirus disease 2019 (COVID-19) pandemic and its potential determinants is limited. Therefore, this multinational study aimed to assess the mental health status of pregnant and breastfeeding women during t...

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  • publication . Article . 2020
    A Comprehensive Mapping of the Druggable Cavities within the SARS-CoV-2 Therapeutically Relevant Proteins by Combining Pocket and Docking Searches as Implemented in Pockets 2.0
    Open Access English
    Authors:
    Gervasoni, Silvia; Vistoli, Giulio; Talarico, Carmine; Manelfi, Candida; Beccari, Andrea R.; Studer, Gabriel; Tauriello, Gerardo; Waterhouse, Andrew Mark; Schwede, Torsten; Pedretti, Alessandro;
    Persistent Identifiers

    pmc: PMC7403965

    pmid: 32708196

    Countries: Switzerland, Italy
    Project: EC | EXSCALATE4CoV (101003551)

    and (4) Conclusions: Even though the presented strategy should require more extended validations, this proved successful in precisely characterizing a set of SARS-CoV-2 druggable binding pockets including both orthosteric and allosteric sites, which are clearly amenable...

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  • publication . Other literature type . Article . 2020
    A Roadmap to Inform Development, Validation and Approval of Digital Mobility Outcomes: The Mobilise-D Approach
    Open Access English
    Authors:
    Lynn Rochester; Claudia Mazzà; Arne Mueller; Brian Caulfield; M. McCarthy; Clemens Becker; Ram R. Miller; Paolo Piraino; Marco Viceconti; Wilhelmus P. Dartee; ...
    Persistent Identifiers

    doi: 10.1159/000512513

    handle: 11250/2726644

    pmc: PMC7768123

    pmid: 33442578

    Publisher: Karger Publishers
    Countries: Italy, Norway, United Kingdom
    Project: EC | MOBILISE-D (820820)

    Abstract Health care has had to adapt rapidly to COVID-19, and this in turn has highlighted a pressing need for tools to facilitate remote visits and monitoring. Digital health technology, including body-worn devices, offers a solution using digital outcomes to measure ...

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  • publication . Article . 2021
    Sanctioned countries in the global COVID-19 vaccination campaign: the forgotten 70%
    Open Access English
    Authors:
    Karl Blanchet; Grégoire Mallard; Erica Moret; Jin Sun;
    Persistent Identifiers

    doi: 10.1186/s13031-021-00404-2

    pmc: PMC8446724

    pmid: 34535155

    Project: EC | PROSANCT (716216)

    AbstractCOVAX, the global initiative on COVID-19 vaccines, has set the target of achieving a COVID-19 vaccination coverage of up to 30% of the population of 135 countries in 2 years. Here, we argue that COVAX should anticipate important and unforeseen challenges with re...

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  • publication . Article . 2018
    The Small-Compound Inhibitor K22 Displays Broad Antiviral Activity against Different Members of the Family Flaviviridae and Offers Potential as a Panviral Inhibitor
    Open Access English
    Authors:
    García-Nicolás, Obdulio; V'kovski, Philip; Vielle, Nathalie J.; Ebert, Nadine; Züst, Roland; Portmann, Jasmine; Stalder, Hanspeter; Gaschen, Véronique; Vieyres, Gabrielle; Stoffel, Michael; ...
    Persistent Identifiers

    doi: 10.1128/aac.01206-18

    pmc: PMC6201103

    pmid: 30181371

    handle: 10033/621549

    Publisher: American Society for Microbiology
    Country: Germany
    Project: EC | ZIKAlliance (734548), SNSF | Host innate immune respon... (310030_173085), EC | COV RESTRIC (748627), SNSF | Zoonotic transmission of ... (320030E-165076), EC | PREDEMICS (278433)

    ABSTRACT The virus family Flaviviridae encompasses several viruses, including (re)emerging viruses which cause widespread morbidity and mortality throughout the world. Members of this virus family are positive-strand RNA viruses and replicate their genome in close assoc...

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  • publication . Article . 2016
    Virus replicon particles expressing porcine reproductive and respiratory syndrome virus proteins elicit immune priming but do not confer protection from viremia in pigs
    Open Access English
    Authors:
    Melanie Eck; Margarita García Durán; Meret E. Ricklin; Samira Locher; Javier Sarraseca; María José Morillo Rodríguez; Kenneth C. McCullough; Artur Summerfield; Gert Zimmer; Nicolas Ruggli;
    Persistent Identifiers

    doi: 10.1186/s13567-016-0318-0

    pmc: PMC4761149

    pmid: 26895704

    Publisher: BioMed Central
    Countries: Switzerland, France
    Project: EC | PORRSCON (245141)

    International audience; AbstractPorcine reproductive and respiratory syndrome virus (PRRSV) is the causative agent of one of the most devastating and economically significant viral disease of pigs worldwide. The vaccines currently available on the market elicit only lim...

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  • publication . Preprint . 2021
    Radius of Gyration as predictor of COVID-19 deaths trend with three-weeks offset
    Open Access English
    Authors:
    Alberto Hernando; David Mateo; Bayer J; Barrios I;
    Persistent Identifiers

    doi: 10.1101/2021.01.30.21250708

    Project: EC | DEMOGRAPHICA (872249)

    AbstractTotal and perimetral lockdowns were the strongest nonpharmaceutical interventions to fight against Covid-19, as well as the with the strongest socioeconomic collateral effects. Lacking a metric to predict the effect of lockdowns in the spreading of COVID-19, aut...

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  • publication . Article . 2021
    Elevated acute phase proteins affect pharmacokinetics in COVID-19 trials:lessons from the CounterCovid - imatinib - study
    Open Access English
    Authors:
    Imke H Bartelink; Pierre M Bet; Nicolas Widmer; Monia Guidi; Erik Duijvelaar; Bram Grob; Richard Honeywell; Amanda Evelo; Ivo P E Tielbeek; Sue D Snape; ...
    Persistent Identifiers

    doi: 10.1002/psp4.12718

    pmc: PMC8646516

    pmid: 34608769

    Country: Netherlands
    Project: EC | Impentri (101005142)

    This study aimed to determine whether published pharmacokinetic (PK) models can adequately predict the PK profile of imatinib in a new indication, such as coronavirus disease 2019 (COVID-19). Total (bound + unbound) and unbound imatinib plasma concentrations obtained fr...

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  • publication . Article . 2021
    EU-PEARL: Changing the paradigm of clinical trials in Europe
    Embargo English
    Authors:
    L Cash-Gibson; JM Pericàs; C Spiertz; E van de Ketterij; E Molero; F Patalano; D Kalra; A Ussi; A Van Dessel; J Genescà;
    Persistent Identifiers

    doi: 10.1093/eurpub/ckab165.657

    Project: EC | EU-PEARL (853966)

    Abstract Issue Recently, innovative clinical trial designs have been proposed, which have the potential to revolutionize clinical research. Whereas classical trials mostly evaluate only one investigational drug, platform trials embed various trials under a shared maste...

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156 research outcomes, page 1 of 16