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44 research outcomes, page 1 of 5
  • publication . Preprint . 2020
    Open Access English
    Authors:
    Peter Czuppon; Florence Débarre; Antonio Gonçalves; Olivier Tenaillon; Alan S. Perelson; Jeremie Guedj; François Blanquart;
    Persistent Identifiers
    Publisher: HAL CCSD
    Country: France
    Project: EC | PolyPath (844369), ANR | TheraCoV (ANR-20-COVI-0018), ANR | TheoGeneDrive (ANR-19-CE45-0009)

    Abstract Repurposed drugs that are immediately available and have a good safety profile constitute a first line of defense against new viral infections. Despite a limited antiviral activity against SARS-CoV-2, several drugs serve as candidates for application, not only ...

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  • publication . Preprint . 2020
    English
    Authors:
    Berger, Loïc; Berger, Nicolas; Bosetti, Valentina; Gilboa, Itzhak; Hansen, Lars,; Jarvis, Christopher; Marinacci, Massimo; Smith, Richard,;
    Publisher: HAL CCSD
    Country: France
    Project: ANR | IPS (ANR-11-IDEX-0003), EC | RISICO (336703), EC | INDIMACRO (670337), ANR | INDUCED (ANR-17-CE03-0008), ANR | ECODEC (ANR-11-LABX-0047)

    Policymaking during a pandemic can be extremely challenging. As COVID-19 is a new disease and its global impacts are unprecedented, decisions need to be made in a highly uncertain, complex and rapidly changing environment. In such a context, in which human lives and the...

  • publication . Article . 2016
    Open Access
    Authors:
    Nicolas eDegauque; Nicolas eDegauque; Nicolas eDegauque; Nicolas eDegauque; Sophie eBrouard; Sophie eBrouard; Sophie eBrouard; Sophie eBrouard; Sophie eBrouard; Sophie eBrouard; ...
    Persistent Identifiers
    Publisher: Frontiers Media SA
    Country: France
    Project: EC | VISICORT (602470), ANR | IGO (ANR-11-LABX-0016)

    International audience; Being able to track donor reactive T cells during the course of organ transplantation is a key to improve the graft survival, to prevent graft dysfunction, and to adapt the immunosuppressive regimen. The attempts of transplant immunologists have ...

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  • publication . Article . 2020
    Open Access
    Authors:
    Ludivine Grzelak; Sarah Temmam; Cyril Planchais; Caroline Demeret; Laura Tondeur; Christèle Huon; Florence Guivel-Benhassine; Isabelle Staropoli; Maxime Chazal; Jérémy Dufloo; ...
    Persistent Identifiers
    Publisher: American Association for the Advancement of Science (AAAS)
    Country: France
    Project: ANR | TIMTAMDEN (ANR-14-CE14-0029), EC | RECoVER (101003589), ANR | CHIKV-Viro-Immuno (ANR-14-CE14-0015)

    It is of paramount importance to evaluate the prevalence of both asymptomatic and symptomatic cases of SARS-CoV-2 infection and their differing antibody response profiles. Here, we performed a pilot study of four serological assays to assess the amounts of anti–SARS-CoV...

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  • publication . Article . 2015
    Open Access English
    Authors:
    Guillaume Castel; Mathilde Couteaudier; Frank Sauvage; Jean-Baptiste Pons; Séverine Murri; Angelina Plyusnina; Dominique Pontier; Jean-François Cosson; Alexander Plyusnin; Philippe Marianneau; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Countries: Finland, France
    Project: EC | ANTIGONE (278976), EC | EDENEXT (261504), ANR | ECOFECT (ANR-11-LABX-0048), ANR | Avenir L.S.E. (ANR-11-IDEX-0007)

    Puumala virus (PUUV) is the agent of nephropathia epidemica (NE), a mild form of hemorrhagic fever with renal syndrome (HFRS) in Europe. NE incidence presents a high spatial variation throughout France, while the geographical distribution of the wild reservoir of PUUV, ...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Loïc Berger; Nicolas Berger; Valentina Bosetti; Itzhak Gilboa; Lars Peter Hansen; Christopher I Jarvis; Massimo Marinacci; Richard D. Smith;
    Persistent Identifiers
    Publisher: HAL CCSD
    Countries: France, United Kingdom, Italy
    Project: EC | INDIMACRO (670337), ANR | INDUCED (ANR-17-CE03-0008), ANR | ECODEC (ANR-11-LABX-0047), ANR | IPS (ANR-11-IDEX-0003), EC | RISICO (336703)

    International audience; Policymaking during a pandemic can be extremely challenging. As COVID-19 is a new disease and its global impacts are unprecedented, decisions are taken in a highly uncertain, complex, and rapidly changing environment. In such a context, in which ...

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  • publication . Article . 2016
    Open Access
    Authors:
    Bioglio L; Génois M; Cl, Vestergaard; Poletto C; Barrat A; Vittoria Colizza;
    Persistent Identifiers
    Publisher: Springer Science and Business Media LLC
    Countries: France, Italy
    Project: EC | PREDEMICS (278433), ANR | Amidex (ANR-11-IDEX-0001), EC | MULTIPLEX (317532), ANR | HarMS-flu (ANR-12-MONU-0018)

    Background The homogeneous mixing assumption is widely adopted in epidemic modelling for its parsimony and represents the building block of more complex approaches, including very detailed agent-based models. The latter assume homogeneous mixing within schools, workplac...

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  • publication . Article . 2020
    Open Access English
    Authors:
    Roche, Mathieu;
    Persistent Identifiers
    Country: France
    Project: EC | MOOD (874850), ANR | DIGITAG (ANR-16-CONV-0004)

    International audience; The vocabulary used in news on a disease such as COVID-19 changes according the period [4]. This aspect is discussed on the basis of MEDISYS-sourced media datasets via two studies. The first focuses on terminology extraction and the second on per...

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  • publication . Preprint . Article . 2018
    Open Access English
    Authors:
    Giancarlo De Luca; Kim Van Kerckhove; Pietro Coletti; Chiara Poletto; Nathalie Bossuyt; Niel Hens; Vittoria Colizza;
    Publisher: Cold Spring Harbor Laboratory
    Countries: France, Belgium, France, France, France
    Project: EC | TransMID (682540), EC | PREDEMICS (278433), ANR | HarMS-flu (ANR-12-MONU-0018)

    Background: School closure is often considered as an option to mitigate influenza epidemics because of its potential to reduce transmission in children and then in the community. The policy is still however highly debated because of controversial evidence. Moreover, the...

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  • publication . Article . Preprint . 2020
    Open Access English
    Authors:
    Laura Di Domenico; Giulia Pullano; Chiara E. Sabbatini; Pierre-Yves Boëlle; Vittoria Colizza;
    Publisher: HAL CCSD
    Country: France
    Project: ANR | SPHINx (ANR-17-CE36-0008), EC | MOOD (874850), ANR | DataRedux (ANR-19-CE46-0008)

    Abstract Background More than half of the global population is under strict forms of social distancing. Estimating the expected impact of lockdown and exit strategies is critical to inform decision makers on the management of the COVID-19 health crisis. Methods We use ...

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44 research outcomes, page 1 of 5