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151 research outcomes, page 1 of 16
  • publication . Article . Other literature type . 2018
    Open Access English
    Authors:
    Bourgarel, Mathieu; Pfukenyi, Davies M.; Boué, Vanina; Talignani, Loïc; Chiweshe, Ngoni; Diop, Fodé; Caron, Alexandre; Matope, Gift; Missé, Dorothée; Liégeois, Florian;
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: ANR | TIMTAMDEN (ANR-14-CE14-0029)

    Highlights • Coronavirus and Paramyxovirus circulate in Hipposideros bat species in Zimbabwe. • Importance of widening viral screening in under-investigated countries • Sentinel surveillance in sites with high zoonotic transmission potential

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  • publication . Preprint . Article . 2021
    Open Access English
    Authors:
    Paul Brandily; Clément Brébion; Simon Briole; Laura Khoury;
    Publisher: HAL CCSD
    Project: ANR | PGSE (ANR-17-EURE-0001)

    Mortality inequalities remain substantial in many countries, and large shocks such as pandemics could amplify them further. The unequal distribution of COVID-19 confirmed cases suggests that this is the case. Yet, evidence on the causal effect of the epidemic on mortali...

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  • publication . Article . 2013
    Open Access English
    Authors:
    Charlotte Lombardi; Maya Ayach; Lionel Beaurepaire; Mélanie Chenon; Jessica Andreani; Raphael Guerois; Isabelle Jupin; Stéphane Bressanelli;
    Persistent Identifiers
    Publisher: Public Library of Science (PLoS)
    Project: ANR | PHOSPHO-POL (ANR-06-BLAN-0062)

    Author Summary Positive-stranded RNA viruses are ultimate parasites. In order to replicate their genome, they first need to invade a host cell and, with usually very limited viral genetic material, subvert the host's molecular machinery. Turnip yellow mosaic virus (TYMV...

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  • publication . Preprint . Article . 2021
    English
    Authors:
    Baunez, Christelle; Degoulet, Mickaël; Luchini, Stéphane; Pintus, Patrick A.; Teschl, Miriam;
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: ANR | AMSE (EUR) (ANR-17-EURE-0020)

    Even though much has been learned about the new pathogen SARS-CoV-2 since the beginning of the COVID-19 pandemic, a lot of uncertainty remains. In this paper we argue that what is important to know under uncertainty is whether harm accelerates and whether health policie...

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  • publication . Preprint . 2020
    Open Access
    Authors:
    Claude Pasquier; Alain Robichon;
    Persistent Identifiers
    Publisher: Cold Spring Harbor Laboratory
    Project: ANR | SIGNALIFE (ANR-11-LABX-0028)

    The role of the RNAi/Dicer/Ago system to degrade RNA viruses has been elusive in mammals, which prompted authors to think that interferon (IFN) synthesis is essential in this clade relegating the RNAi defense strategy against viral infection as accessory function. We ex...

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  • publication . Article . 2015
    Open Access English
    Authors:
    Clément Cocita; Rachel Guiton; Gilles Bessou; Lionel Chasson; Marilyn Boyron; Karine Crozat; Marc Dalod;
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: ANR | PSL (ANR-10-IDEX-0001), ANR | Amidex (ANR-11-IDEX-0001)

    In mice, plasmacytoid dendritic cells (pDC) and natural killer (NK) cells both contribute to resistance to systemic infections with herpes viruses including mouse Cytomegalovirus (MCMV). pDCs are the major source of type I IFN (IFN-I) during MCMV infection. This respons...

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  • publication . Article . Other literature type . 2018
    Open Access English
    Authors:
    Mathieu, Cyrille; Porotto, Matteo; Figueira, Tiago N; Horvat, Branka; Moscona, Anne;
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: NIH | MOLECULAR BASIS FOR PARAI... (5R29AI031971-03), NIH | Design of CNS-targeted pe... (5R33AI101333-04), ANR | ECOFECT (ANR-11-LABX-0048), NIH | Engineering protease-resi... (5R01AI114736-04), ANR | Avenir L.S.E. (ANR-11-IDEX-0007)

    International audience; Background. The emerging zoonotic paramyxovirus Nipah virus (NiV) causes severe respiratory and neurological disease inhumans, with high fatality rates. Nipah virus can be transmitted via person-to-person contact, posing a high risk for epidemic ...

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  • publication . Article . 2019
    Open Access English
    Authors:
    Bernard-Stoecklin, Sibylle; Nikolay, Birgit; Assiri, Abdullah; Bin Saeed, Abdul Aziz; Ben Embarek, Peter Karim; El Bushra, Hassan; Ki, Moran; Malik, Mamunur Rahman; Fontanet, Arnaud; Cauchemez, Simon; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: ANR | INCEPTION (ANR-16-CONV-0005)

    International audience; Since its emergence in 2012, 2,260 cases and 803 deaths due to Middle East respiratory syndrome coronavirus (MERS-CoV) have been reported to the World Health Organization. Most cases were due to transmission in healthcare settings, sometimes caus...

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  • publication . Article . Preprint . 2020
    Open Access English
    Authors:
    Frédéric Lemoine; Luc Blassel; Jakub Voznica; Olivier Gascuel;
    Publisher: HAL CCSD
    Project: ANR | PRAIRIE (ANR-19-P3IA-0001)

    AbstractMotivationThe first cases of the COVID-19 pandemic emerged in December 2019. Until the end of February 2020, the number of available genomes was below 1,000, and their multiple alignment was easily achieved using standard approaches. Subsequently, the availabili...

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  • publication . Article . 2015
    Open Access English
    Authors:
    Anne Laure Pham-Hung d'Alexandry d'Orengiani; Lidia Duarte; Nicole Pavio; Sophie Le Poder;
    Publisher: Elsevier B.V.
    Project: ANR | EPICOREM (ANR-13-BSV3-0013)

    Highlights • Accessory proteins of coronaviruses play a role in virus adaptation to a new host. • Some FCoV harbour truncated gp3 proteins, an accessory protein peculiar of CCoV-I. • Deletions of gp3 do not influence their basic features. • Deletions impact the expressi...

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151 research outcomes, page 1 of 16