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4 Research products, page 1 of 1

  • COVID-19
  • French National Research Agency (ANR)
  • IPS
  • English
  • Hal-Diderot

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  • English
    Authors: 
    Boyer, Pierre,; Gerschel, Elie; Raj, Anasuya;
    Publisher: HAL CCSD
    Country: France
    Project: ANR | IPS (ANR-11-IDEX-0003)

    Summary:The European economic union is incomplete, which makes it vulnerable to macroeconomic shocks. The opportunity to move forward in the integration process was highly debated even before the Covid-19 crisis.Yet the diverging views among countries and political groups are often considered as an obstacle on the path to required agreements for completing the Economic and Monetary Union (EMU). We present the results of a survey conducted in 2018 among members of national parliaments (MPs) in France, Germany and Italy on European integration in policy fields related to risk-sharing and budgetary institutions, asking for their opinion on proposals such as the creation of a European Unemployment Insurance (EUI), Eurobonds, or an EU tax. We find that nationality and political groups are key determinants of support for such proposals, the latter being the strongest. We describe how opinions are divided and try to identify policy proposals which could gather enough political support. The agreement reached on July 21st, 2020 at the last European summit includes financial transfers between States and the creation of Eurobonds, thus representing an important institutional move and an application of some of the reforms suggested by our survey. Yet what has been decided upon is only temporary and leaves open the question of the future of European integration.Key points: At first glance, the answers show diverging opinions on most questions between countries with Italy supporting more integration, and Germany opposing it for most proposals. France has an intermediate position, leaning towards Italy. A breakdown of the results by party affiliation shows a more nuanced picture. For cross-country comparisons, we build a party indicator using the affiliation of national parties to European political groups. National MPs associated with the group of Socialists and Democrats (S&D) at the European level show strong support for the creation of new fiscal institutions and a new EU tax, and for risk sharing institutions (European Unemployment Insurance, Eurobonds). On the contrary, MPs associated with the European People’s Party (EPP) are mildly positive or against risk-sharing and fiscal institutions. National MPs affiliated to Renew Europe hold similar views to S&D MPs, but are less supportive of risk-sharing mechanisms. There is a substantial diversity of positions between the German AfD, the Italian Lega and the 5-star movement: the three parties have diverging views on the future of integration. Our econometric analysis shows that party affiliations have more explanatory power than nationality for all questions. This clearly shows that outcomes of national parliamentary elections could change the overall support for any issue.; Summary:The European economic union is incomplete, which makes it vulnerable to macroeconomic shocks. The opportunity to move forward in the integration process was highly debated even before the Covid-19 crisis.Yet the diverging views among countries and political groups are often considered as an obstacle on the path to required agreements for completing the Economic and Monetary Union (EMU). We present the results of a survey conducted in 2018 among members of national parliaments (MPs) in France, Germany and Italy on European integration in policy fields related to risk-sharing and budgetary institutions, asking for their opinion on proposals such as the creation of a European Unemployment Insurance (EUI), Eurobonds, or an EU tax. We find that nationality and political groups are key determinants of support for such proposals, the latter being the strongest. We describe how opinions are divided and try to identify policy proposals which could gather enough political support. The agreement reached on July 21st, 2020 at the last European summit includes financial transfers between States and the creation of Eurobonds, thus representing an important institutional move and an application of some of the reforms suggested by our survey. Yet what has been decided upon is only temporary and leaves open the question of the future of European integration.Key points: At first glance, the answers show diverging opinions on most questions between countries with Italy supporting more integration, and Germany opposing it for most proposals. France has an intermediate position, leaning towards Italy. A breakdown of the results by party affiliation shows a more nuanced picture. For cross-country comparisons, we build a party indicator using the affiliation of national parties to European political groups. National MPs associated with the group of Socialists and Democrats (S&D) at the European level show strong support for the creation of new fiscal institutions and a new EU tax, and for risk sharing institutions (European Unemployment Insurance, Eurobonds). On the contrary, MPs associated with the European People’s Party (EPP) are mildly positive or against risk-sharing and fiscal institutions. National MPs affiliated to Renew Europe hold similar views to S&D MPs, but are less supportive of risk-sharing mechanisms. There is a substantial diversity of positions between the German AfD, the Italian Lega and the 5-star movement: the three parties have diverging views on the future of integration. Our econometric analysis shows that party affiliations have more explanatory power than nationality for all questions. This clearly shows that outcomes of national parliamentary elections could change the overall support for any issue.

  • English
    Authors: 
    Berger, Loïc; Berger, Nicolas; Bosetti, Valentina; Gilboa, Itzhak; Hansen, Lars,; Jarvis, Christopher; Marinacci, Massimo; Smith, Richard,;
    Publisher: HAL CCSD
    Country: France
    Project: EC | INDIMACRO (670337), ANR | INDUCED (ANR-17-CE03-0008), ANR | ECODEC (ANR-11-LABX-0047), ANR | IPS (ANR-11-IDEX-0003), EC | RISICO (336703)

    Policymaking during a pandemic can be extremely challenging. As COVID-19 is a new disease and its global impacts are unprecedented, decisions need to be made in a highly uncertain, complex and rapidly changing environment. In such a context, in which human lives and the economy are at stake, we argue that using ideas and constructs from modern decision theory, even informally, will make policymaking more a responsible and transparent process.

  • Publication . Article . 2021
    Open Access English
    Authors: 
    Loïc Berger; Nicolas Berger; Valentina Bosetti; Itzhak Gilboa; Lars Peter Hansen; Christopher I Jarvis; Massimo Marinacci; Richard D. Smith;
    Publisher: HAL CCSD
    Countries: United Kingdom, Italy, United Kingdom, France, Italy
    Project: ANR | IPS (ANR-11-IDEX-0003), EC | RISICO (336703), ANR | INDUCED (ANR-17-CE03-0008), EC | INDIMACRO (670337), ANR | ECODEC (ANR-11-LABX-0047), ANR | IPS (ANR-11-IDEX-0003), EC | RISICO (336703), ANR | INDUCED (ANR-17-CE03-0008), EC | INDIMACRO (670337), ANR | ECODEC (ANR-11-LABX-0047)

    International audience; Policymaking during a pandemic can be extremely challenging. As COVID-19 is a new disease and its global impacts are unprecedented, decisions are taken in a highly uncertain, complex, and rapidly changing environment. In such a context, in which human lives and the economy are at stake, we argue that using ideas and constructs from modern decision theory, even informally, will make policymaking a more responsible and transparent process.

  • Open Access English
    Authors: 
    Yu Wu; Valérie Pons; Amélie Goudet; Laetitia Panigai; Annette Fischer; Jo-Ana Herweg; Sabrina Kali; Robert A. Davey; Jérôme Laporte; Céline Bouclier; +19 more
    Publisher: HAL CCSD
    Countries: France, France, France, Germany, France
    Project: NIH | Receptor Trafficking in E... (5R01AI063513-05), ANR | IPS (ANR-11-IDEX-0003), NHMRC | Blue Mountains Cohort Stu... (457349)

    International audience; Intracellular pathogenic microorganisms and toxins exploit host cell mechanisms to enter, exert their deleterious effects as well as hijack host nutrition for their development. A potential approach to treat multiple pathogen infections and that should not induce drug resistance is the use of small molecules that target host components. We identified the compound 1-adamantyl (5-bromo-2-methoxybenzyl) amine (ABMA) from a cell-based high throughput screening for its capacity to protect human cells and mice against ricin toxin without toxicity. This compound efficiently protects cells against various toxins and pathogens including viruses, intracellular bacteria and parasite. ABMA provokes Rab7-positive late endosomal compartment accumulation in mammalian cells without affecting other organelles (early endosomes, lysosomes, the Golgi apparatus, the endoplasmic reticulum or the nucleus). As the mechanism of action of ABMA is restricted to host-endosomal compartments, it reduces cell infection by pathogens that depend on this pathway to invade cells. ABMA may represent a novel class of broad-spectrum compounds with therapeutic potential against diverse severe infectious diseases.