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The following results are related to COVID-19. Are you interested to view more results? Visit OpenAIRE - Explore.
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7 research outcomes, page 1 of 1
  • publication . Preprint . Article . 2022
    Open Access English
    Authors:
    Nilima Dinesh Kumar; Bram M. ter Ellen; Ellen M Bouma; Berit Troost; Denise P. I. van de Pol; Heidi van der Ende-Metselaar; Djoke van Gosliga; Leonie Apperloo; Orestes A Carpaij; Maarten van den Berge; ...
    Publisher: American Society for Microbiology
    Country: Netherlands
    Project: EC | PRONKJEWAIL (713660)

    AbstractAntiviral therapies are urgently needed to treat and limit the development of severe COVID-19 disease. Ivermectin, a broad-spectrum anti-parasitic agent, has been shown to have anti-SARS-CoV-2 activity in Vero cells at a concentration of 5 µM. These in vitro res...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Bram M. ter Ellen; Nilima Dinesh Kumar; Ellen M Bouma; Berit Troost; Denise P. I. van de Pol; Heidi van der Ende-Metselaar; Leonie Apperloo; Djoke van Gosliga; Maarten van den Berge; Martijn C. Nawijn; ...
    Country: Netherlands
    Project: EC | PRONKJEWAIL (713660), EC | EVA-GLOBAL (871029)

    The current COVID-19 pandemic is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and has an enormous impact on human health and economy. In search for therapeutic options, researchers have proposed resveratrol, a food supplement with known antivir...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Rick Oerlemans; Angel J Ruiz-Moreno; Yingying Cong; Nilima Dinesh Kumar; Marco A. Velasco-Velázquez; Constantinos G. Neochoritis; Jolanda Smith; Fulvio Reggiori; Matthew Groves; Alexander Dömling;
    Country: Netherlands
    Project: EC | PRONKJEWAIL (713660), EC | DRIVE (765912)

    The rapid growth of COVID-19 cases is causing an increasing death toll and also paralyzing the world economy. De novo drug discovery takes years to move from idea and/or pre-clinic to market, and it is not a short-term solution for the current SARS-CoV-2 pandemic. Drug ...

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  • publication . Article . Other literature type . Review . 2020
    Open Access English
    Authors:
    Bahaa Abu-Raya; Giovanni Battista Migliori; Miguel O'Ryan; Kathryn Edwards; Antoni Torres; Jan-Willem Alffenaar; Jan-Willem Alffenaar; Jan-Willem Alffenaar; Anne-Grete Märtson; Rosella Centis; ...
    Publisher: Frontiers Media S.A.
    Countries: Belgium, Netherlands
    Project: EC | PRONKJEWAIL (713660)

    Coronavirus disease 2019 (COVID-19) is a rapidly evolving, highly transmissible, and potentially lethal pandemic caused by a novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). As of June 11 2020, more than 7,000,000 COVID-19 cases have been...

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  • publication . Preprint . Article . 2019
    Open Access English
    Authors:
    Alessia Landi; Muriel Mari; Tobias Wolf; Svenja Kleiser; Christine Gretzmeier; Isabel Wilhelm; Dimitra Kiritsi; Roland Thuenauer; Roger Geiger; Alexander Nyström; ...
    Publisher: Life Science Alliance LLC
    Country: Netherlands
    Project: EC | LEC&LIP2INVADE (282105), NWO | A three-dimensional look ... (2300175771), EC | DRIVE (765912), EC | PRONKJEWAIL (713660)

    Lectins are glycan-binding proteins with no catalytic activity and ubiquitously expressed in nature. Numerous bacteria use lectins to efficiently bind to epithelia, thus facilitating tissue colonisation. Wounded skin is one of the preferred niches for Pseudomonas aerugi...

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  • other research product . Other ORP type . 2017
    Open Access English
    Authors:
    Cong, Yingying; Verlhac, Pauline; Reggiori, Fulvio;
    Project: NWO | A three-dimensional look ... (2300175771), EC | PRONKJEWAIL (713660), SNSF | ER-phagy mechanisms to ma... (CRSII3_154421)

    Autophagy is a conserved intracellular catabolic pathway that allows cells to maintain homeostasis through the degradation of deleterious components via specialized double-membrane vesicles called autophagosomes. During the past decades, it has been revealed that numero...

  • publication . Article . 2017
    Open Access English
    Authors:
    Yingying Cong; Pauline Verlhac; Fulvio Reggiori;
    Country: Netherlands
    Project: EC | PRONKJEWAIL (713660), NWO | A three-dimensional look ... (2300175771), SNSF | ER-phagy mechanisms to ma... (CRSII3_154421)

    Autophagy is a conserved intracellular catabolic pathway that allows cells to maintain homeostasis through the degradation of deleterious components via specialized double-membrane vesicles called autophagosomes. During the past decades, it has been revealed that numero...

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7 research outcomes, page 1 of 1