The 2019 outbreak of coronavirus disease (COVID-19) in Wuhan (Hubei province of China) has given rise to a pandemic spread of virus, more than 240 million incidences and a death toll larger than 5 million people. COVID-19 has set off large efforts in research, therapy a...

During the conduct of the study, the following is reported: Dr. Berry reports being employee with ownership role at Berry Consultants (receives payments for statistical modeling and design of REMAP-CAP). Dr. Castillo reports grants from DOST PCHRD. Dr. Daly reports gran...

While vaccines that protect against SARS-CoV-2 are being approved, the number of available doses is limited as it may take months until the production of vaccines can meet the actual demand. The majority of available SARS-CoV-2 vaccines elicits strong immune responses w...

IntroductionBCG vaccination modulates immune responses to unrelated pathogens. This off-target effect could reduce the impact of emerging pathogens. As a readily available, inexpensive intervention that has a well-established safety profile, BCG is a good candidate for ...

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in over 100 million infections and millions of deaths. Effective vaccines remain the best hope of curtailing SARS-CoV-2 transmission, morbidity, and mortality. The vaccines ...

Patients with coronavirus disease 2019 (COVID-19) may experience a cytokine storm with elevated interleukin-6 (IL-6) levels in response to severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2). IL-6 suppresses hepatic enzymes, including CYP3A; however, the effect...

Testing, contact tracing, and isolation (TTI) is an epidemic management and control approach that is difficult to implement at scale. Here we demonstrate a scalable improvement to TTI that uses data assimilation (DA) on a contact network to learn about individual risks ...

It is well established that burnout in medical students is associated with depression and anxiety at a syndromal level. Moreover, there is an ongoing debate about the extent to which burnout overlaps with depression and anxiety. The emerging network approach to psychopa...

We examined the longitudinal course of, and pre- and during-pandemic risk factors for, self-injury and domestic physical violence perpetration in young adults during the COVID-19 pandemic. Data came from a Swiss longitudinal study (N = 786, age ˜22 in 2020), with one pr...

This study explored characteristics of young adults' solidarity during the Covid-19 pandemic by identifying three different profiles, characterized by low (23%), average (54%), and high solidarity (23%). Based on longitudinal Swiss panel data (NT1 = 797, Mage T1 = 12.15...