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COVID-19 Elsevier

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COVID-19 Elsevier

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52 research outcomes, page 1 of 6
  • publication . Article . 2013
    Open Access English
    Authors:
    Cheng, Vincent C.C.; Chan, Jasper F.W.; To, Kelvin K.W.; Yuen, K.Y.;
    Persistent Identifiers
    Publisher: The Authors. Published by Elsevier B.V.

    AbstractThe outbreak of severe acute respiratory syndrome (SARS) in 2003 was the first emergence of an important human pathogen in the 21st century. Responding to the epidemic provided clinicians with extensive experience in diagnosing and treating a novel respiratory v...

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  • publication . Other literature type . Article . 2010
    Open Access English
    Authors:
    Ritchie, Gayle; Harvey, David J.; Feldmann, Friederike; Stroeher, Ute; Feldmann, Heinz; Royle, Louise; Dwek, Raymond A.; Rudd, Pauline M.;
    Persistent Identifiers
    Project: WT

    AbstractN-glycans were released from the SARS coronavirus (SARS-CoV) spike glycoprotein produced in Vero E6 cells and their structures were determined by a combination of matrix-assisted laser desorption/ionization (MALDI) mass spectrometry, negative ion electrospray co...

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  • publication . Article . 2003
    Open Access
    Authors:
    Wu, Qingfa; Zhang, Yilin; Lu, Hong; Wang, Jing; He, Ximiao; Liu, Yong; Ye, Chen; Lin, Wei; Hu, Jianfei; Ji, Jia; ...

    None: The E (envelope) protein is the smallest structural protein in all coronaviruses and is the only viral structural protein in which no variation has been detected. We conducted genome sequencing and phylogenetic analyses of SARS-CoV. Based on genome sequencing, we ...

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  • publication . Article . 2003
    Open Access English
    Authors:
    Bi, Shengli; Qin, E’de; Xu, Zuyuan; Li, Wei; Wang, Jing; Hu, Yongwu; Liu, Yong; Duan, Shumin; Hu, Jianfei; Han, Yujun; ...
    Publisher: Beijing Institute of Genomics, the Chinese Academy of Sciences and the Genetics Society of China. Production and hosting by Elsevier B.V.

    Beijing has been one of the epicenters attacked most severely by the SARS-CoV (severe acute respiratory syndrome-associated coronavirus) since the first patient was diagnosed in one of the city’s hospitals. We now report complete genome sequences of the BJ Group, includ...

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  • publication . Article . 2003
    Open Access English
    Authors:
    Li, Jingxiang; Luo, Chunqing; Deng, Yajun; Han, Yujun; Tang, Lin; Wang, Jing; Ji, Jia; Ye, Jia; Jiang, Fanbo; Xu, Zhao; ...
    Publisher: Elsevier

    The corona-like spikes or peplomers on the surface of the virion under electronic microscope are the most striking features of coronaviruses. The S (spike) protein is the largest structural protein, with 1,255 amino acids, in the viral genome. Its structure can be divid...

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  • publication . Article . 2005
    Open Access English
    Authors:
    Chang, Chung-ke; Sue, Shih-Che; Yu, Tsan-hung; Hsieh, Chiu-Min; Tsai, Cheng-Kun; Chiang, Yen-Chieh; Lee, Shin-jye; Hsiao, Hsin-hao; Wu, Wen-Jin; Chang, Chi-Fon; ...
    Persistent Identifiers
    Publisher: Published by Elsevier B.V.

    AbstractWe have employed NMR to investigate the structure of SARS coronavirus nucleocapsid protein dimer. We found that the secondary structure of the dimerization domain consists of five α helices and a β-hairpin. The dimer interface consists of a continuous four-stran...

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  • publication . Article . 2003
    Open Access
    Authors:
    Xu, Zuyuan; Zhang, Haiqing; Tian, Xiangjun; Ji, Jia; Li, Wei; Li, Yan; Tian, Wei; Han, Yujun; Wang, Lili; Zhang, Zizhang; ...

    The R (replicase) protein is the uniquely defined non-structural protein (NSP) responsible for RNA replication, mutation rate or fidelity, regulation of transcription in coronaviruses and many other ssRNA viruses. Based on our complete genome sequences of four isolates ...

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  • publication . Article . 2005
    Open Access English
    Authors:
    Baranov, Pavel V.; Henderson, Clark M.; Anderson, Christine B.; Gesteland, Raymond F.; Atkins, John F.; Howard, Michael T.;
    Persistent Identifiers
    Publisher: Elsevier Inc.
    Project: NIH | RECODING--DYNAMIC REPROGR... (2R01GM048152-05A1)

    AbstractProgrammed ribosomal frameshifting is an essential mechanism used for the expression of orf1b in coronaviruses. Comparative analysis of the frameshift region reveals a universal shift site U_UUA_AAC, followed by a predicted downstream RNA structure in the form o...

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  • publication . Article . 2004
    Open Access English
    Authors:
    Mortola, Eduardo; Roy, Polly;
    Persistent Identifiers
    Publisher: Federation of European Biochemical Societies. Published by Elsevier B.V.

    AbstractVirus-like particles (VLPs) produced by recombinant expression of the major viral structural proteins could be an attractive method for severe acute respiratory syndrome (SARS) control. In this study, using the baculovirus system, we generated recombinant viruse...

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  • publication . Article . Other literature type . 2008
    Open Access
    Authors:
    Mossel, Eric C.; Wang, Jieru; Jeffers, Scott; Edeen, Karen E.; Wang, Shuanglin; Cosgrove, Gregory P.; Funk, C. Joel; Manzer, Rizwan; Miura, Tanya A.; Pearson, Leonard D.; ...
    Persistent Identifiers
    Publisher: Elsevier BV
    Project: NIH | Alveolar Type II Cells in... (5R01HL029891-24), NIH | Type II Pneumocyte Intera... (5P01AI059576-05)

    AbstractSevere acute respiratory syndrome (SARS) is a disease characterized by diffuse alveolar damage. We isolated human alveolar type II cells and maintained them in a highly differentiated state. Type II cell cultures supported SARS-CoV replication as evidenced by RT...

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52 research outcomes, page 1 of 6