Quick search
Advanced search in
Research outcomes
Field to searchTerm
Add rule
Filters (1)
The following results are related to COVID-19. Are you interested to view more results? Visit OpenAIRE - Explore.
Download Results
8 research outcomes, page 1 of 1
  • publication . Article . Other literature type . 2004
    Open Access English
    Authors:
    Meyers, Lauren Ancel; Pourbohloul, Babak; Newman, M.E.J.; Skowronski, Danuta M.; Brunham, Robert C.;
    Persistent Identifiers
    Publisher: Elsevier Ltd.
    Project: NSF | Evolving Better Biofilms:... (0303636), NSF | Structure and Dynamics of... (0234188), CIHR

    Abstract Many infectious diseases spread through populations via the networks formed by physical contacts among individuals. The patterns of these contacts tend to be highly heterogeneous. Traditional “compartmental” modeling in epidemiology, however, assumes that popul...

    Add to ORCID
  • publication . Other literature type . Article . 2006
    Open Access
    Authors:
    Bhardwaj, Kanchan; Sun, Jingchuan; Holzenburg, Andreas; Guarino, Linda A.; Kao, C. Cheng;
    Persistent Identifiers
    Publisher: Elsevier BV
    Project: NSF | Mechanism of Viral RNA-de... (0332259)

    The emerging disease SARS is caused by a novel coronavirus that encodes several unusual RNA-processing enzymes, including non-structural protein 15 (Nsp15), a hexameric endoribonuclease that preferentially cleaves at uridine residues.1., 2., 3. How Nsp15 recognizes and ...

    Add to ORCID
  • publication . Article . 2013
    Open Access
    Authors:
    Pillaiyar Thanigaimalai; Sho Konno; Takehito Yamamoto; Yuji Koiwai; Akihiro Taguchi; Kentaro Takayama; Fumika Yakushiji; Kenichi Akaji; Shen En Chen; Aurash Naser-Tavakolian; ...
    Persistent Identifiers
    Publisher: Elsevier BV
    Project: NSF | Inhibition of Protein-Pro... (1157506), NIH | STRUCTURE BASED THERMODYN... (3R01GM057144-06S1), NIH | Structure-Based Antagonis... (3P01GM056550-16S1)

    We report the design and synthesis of a series of dipeptide-type inhibitors with novel P3 scaffolds that display potent inhibitory activity against SARS-CoV 3CLpro. A docking study involving binding between the dipeptidic lead compound 4 and 3CLpro suggested the modific...

    Add to ORCID
  • publication . Preprint . Article . Other literature type . 2020
    Open Access English
    Authors:
    Lodge, Evans K.; Schatz, Annakate M.; Drake, John M.;
    Persistent Identifiers
    Publisher: Cold Spring Harbor Laboratory
    Project: NSF | REU Site: Population Biol... (1156707), NIH | Forecasting tipping point... (1U01GM110744-01)

    Background During outbreaks of emerging and re-emerging infections, the lack of effective drugs and vaccines increases reliance on non-pharmacologic public health interventions and behavior change to limit human-to-human transmission. Interventions that increase the spe...

    Add to ORCID
  • publication . Article . 2015
    Open Access English
    Authors:
    Gerardo Chowell; Fatima Abdirizak; Sunmi Lee; Jonggul Lee; Eunok Jung; Hiroshi Nishiura; Cécile Viboud;
    Persistent Identifiers
    Publisher: BioMed Central
    Project: UKRI | US-UK EEID Collab: Risks ... (BB/M008894/1), NSF | US-UK Collab: Risks of An... (1414374), NSF | RAPID: Understanding the ... (1518939)

    Background The Middle East respiratory syndrome (MERS) coronavirus has caused recurrent outbreaks in the Arabian Peninsula since 2012. Although MERS has low overall human-to-human transmission potential, there is occasional amplification in the healthcare setting, a pat...

    Add to ORCID
  • publication . Article . Other literature type . 2019
    Open Access
    Authors:
    Chowell, Gerardo; Tariq, Amna; Hyman, James M.;
    Persistent Identifiers
    Publisher: Springer Science and Business Media LLC
    Project: NSF | US-UK Collab: Risks of An... (1414374)

    Background Simple phenomenological growth models can be useful for estimating transmission parameters and forecasting epidemic trajectories. However, most existing phenomenological growth models only support single-peak outbreak dynamics whereas real epidemics often dis...

    Add to ORCID
  • publication . Article . Other literature type . 2019
    Open Access
    Authors:
    Abdirizak, Fatima; Lewis, Rayleen; Chowell, Gerardo;
    Persistent Identifiers
    Publisher: Springer Science and Business Media LLC
    Project: UKRI | US-UK EEID Collab: Risks ... (BB/M008894/1), NSF | US-UK Collab: Risks of An... (1414374)

    <jats:title>Abstract</jats:title> <jats:sec> <jats:title>Background</jats:title> <jats:p>Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS) are two coronaviruses with demonstrated potential to generate significant nosocomial outbreaks. ...

    Add to ORCID
  • publication . Article . Preprint . 2020
    Open Access English
    Authors:
    Baltazar Espinoza; Carlos Castillo-Chavez; Charles Perrings;
    Publisher: Public Library of Science
    Project: NSF | US-UK Collab: Risks of An... (1414374)

    Background: Mobility restrictions - trade and travel bans, border closures and, in extreme cases, area quarantines or cordons sanitaires- are among the most widely used measures to control infectious diseases. Restrictions of this kind were important in the response to ...

    Add to ORCID
8 research outcomes, page 1 of 1