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1,159 Research products, page 1 of 116

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  • Open Access
    Authors: 
    Madeso, Ferengki; Arsyad, Dian Sidik; Rismayanti;
    Country: Indonesia

    Petugas Kantor Kesehatan Pelabuhan (KKP) Kelas I Makasar sebagai garda terdepan kesehatan dengan tugas fungsi cegah tangkal penyakit maupun kejadian kesehatan masyarakat yang dapat meresahkan dunia dengan mendeteksi,dan melakukan respon cepat semua kasus penyakit. Dalam melaksanakan tugas mendeteksi dan respon cepat suatu penyakit petugas dituntut memiliki pengetahuan yang tinggi dan sikap yang baik terhadap suatu penyakit tertentu, termasuk penyakit MERS-CoV, Meningitis Meningokokus dan AIDS. Penelitian bertujuan untuk mengetahui hubungan antara pengetahuan dan sikap petugas dengan tindakan pencegahan penyakit menular di KKP Kelas I Makassar. Jenis penelitian yang digunakan adalah observasi analitik dengan pendekatan cross sectional study dengan besar sampel 30 responden penarikan sampel menggunakan exhaustive sampling. Selanjutnya pengolahan dan analisis data menggunakan komputerisasi. Analisis hubungan antar variabel menggunakan uji chi-square menggunakan fisher exact test pada tingkat kemaknaan 0,05 dan besarnya hubungan menggunakan uji phi (??). Hasil penelitian menunjukan bahwa ada hubungan antara pengetahuan petugas dengan tindakan penyakit menular (p=0,009; ??=0,604), dan ada hubungan antara sikap petugas dengan tindakan penyakit menular (p=0,007; ??=0,802). Kesimpulan dari penelitian bahwa ada hubungan antara pengetahuan dan sikap petugas dengan tindakan pencegahan penyakit menular di KKP Kelas I Makassar. Kata Kunci: Penyakit menular, MERS-CoV, meningitis, aids

  • Authors: 
    Virlogeux, Victor; Park, Minah; Wu, Joseph Tsz Kei; Cowling, Benjamin J.;
    Publisher: Dryad Digital Repository
  • Authors: 
    Virlogeux, Victor; Park, Minah; Wu, Joseph Tsz Kei; Cowling, Benjamin J.;
    Publisher: Dryad Digital Repository
  • Closed Access English
    Country: Netherlands
  • English
    Authors: 
    (:Unkn) Unknown;
    Publisher: My University

    © 2019 Society for Risk Analysis Middle Eastern respiratory syndrome, an emerging viral infection with a global case fatality rate of 35.5%, caused major outbreaks first in 2012 and 2015, though new cases are continuously reported around the world. Transmission is believed to mainly occur in healthcare settings through aerosolized particles. This study uses Quantitative Microbial Risk Assessment to develop a generalizable model that can assist with interpreting reported outbreak data or predict risk of infection with or without the recommended strategies. The exposure scenario includes a single index patient emitting virus-containing aerosols into the air by coughing, leading to short- and long-range airborne exposures for other patients in the same room, nurses, healthcare workers, and family visitors. Aerosol transport modeling was coupled with Monte Carlo simulation to evaluate the risk of MERS illness for the exposed population. Results from a typical scenario show the daily mean risk of infection to be the highest for the nurses and healthcare workers (8.49 × 10−4 and 7.91 × 10−4, respectively), and the lowest for family visitors and patients staying in the same room (3.12 × 10−4 and 1.29 × 10−4, respectively). Sensitivity analysis indicates that more than 90% of the uncertainty in the risk characterization is due to the viral concentration in saliva. Assessment of risk interventions showed that respiratory masks were found to have a greater effect in reducing the risks for all the groups evaluated (>90% risk reduction), while increasing the air exchange was effective for the other patients in the same room only (up to 58% risk reduction).

  • Research data . 2015
    Authors: 
    Virlogeux, Victor; Park, Minah; Wu, Joseph Tsz Kei; Cowling, Benjamin J.;
    Publisher: Dryad Digital Repository
  • Open Access English
    Authors: 
    Algaissi, Abdullah; Hashem, Anwar M.;

    The microneutralization (MN) assay is a standard and important technique in virology, immunology, and epidemiology. It is a highly specific and sensitive assay for evaluating virus-specific neutralizing antibodies (nAbs) in human and animal sera. It provides the most precise answer to whether or not an individual or animal has antibodies that can neutralize or inhibit the infectivity of a specific virus strain. However, using live virus-based MN assay might require working under high containment facilities especially when dealing with high-risk pathogens such as the Middle East respiratory syndrome-coronavirus (MERS-CoV). In this chapter, we describe the isolation, amplification, and titration of MERS-CoV, as well as detailed MN assay to measure nAb levels in sera from different mammalian species.

  • Authors: 
    Virlogeux, Victor; Park, Minah; Wu, Joseph Tsz Kei; Cowling, Benjamin J.;
    Publisher: Dryad Digital Repository
  • Research data . 2015
    Authors: 
    Virlogeux, Victor; Park, Minah; Wu, Joseph Tsz Kei; Cowling, Benjamin J.;
    Publisher: Dryad Digital Repository

    This data file contains individual information on laboratory-confirmed MERS cases in South Korea in 2015.

  • Authors: 
    Virlogeux, Victor; Park, Minah; Wu, Joseph Tsz Kei; Cowling, Benjamin J.;
    Publisher: Dryad Digital Repository