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141 Research products, page 1 of 15

  • COVID-19
  • EU
  • HAL Descartes

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  • Open Access
    Authors: 
    Gaymard, Alexandre; Bosetti, Paolo; Feri, Adeline; Destras, Gregory; Enouf, Vincent; Andronico, Alessio; Burrel, Sonia; Behillil, Sylvie; Sauvage, Claire; Bal, Antonin; +97 more
    Publisher: European Centre for Disease Control and Prevention (ECDC)
    Country: France
    Project: EC | RECoVER (101003589)

    International audience; The emergence of SARS-CoV-2 variant 20I/501Y.V1 (VOC-202012/1 or GR/501Y.V1) is concerning given its increased transmissibility. We reanalysed 11,916 PCR-positive tests (41% of all positive tests) performed on 7-8 January 2021 in France. The prev...

  • Open Access
    Authors: 
    Théo Jaffrelot Inizan; Frédéric Célerse; Olivier Adjoua; Dina El Ahdab; Luc-Henri Jolly; Chengwen Liu; Pengyu Ren; Matthieu Montes; Nathalie Lagarde; Louis Lagardère; +2 more
    Publisher: American Chemical Society (ACS)
    Country: France
    Project: EC | EMC2 (810367)

    We provide an unsupervised adaptive sampling strategy capable of producing μs-timescale molecular dynamics (MD) simulations of large biosystems using many-body polarizable force fields (PFFs). The global exploration problem is decomposed into a set of separate MD trajec...

  • Open Access English
    Authors: 
    Nicolas eDegauque; Nicolas eDegauque; Nicolas eDegauque; Nicolas eDegauque; Sophie eBrouard; Sophie eBrouard; Sophie eBrouard; Sophie eBrouard; Sophie eBrouard; Sophie eBrouard; +4 more
    Publisher: Frontiers Media S.A.
    Country: France
    Project: ANR | IGO (ANR-11-LABX-0016), EC | VISICORT (602470)

    International audience; Being able to track donor reactive T cells during the course of organ transplantation is a key to improve the graft survival, to prevent graft dysfunction, and to adapt the immunosuppressive regimen. The attempts of transplant immunologists have ...

  • Publication . Part of book or chapter of book . 2021
    Open Access English
    Authors: 
    Giuliano Bobba; Nicolas Hubé;
    Publisher: HAL CCSD
    Countries: France, Italy, France
    Project: EC | DEMOS (822590)

    It is widely believed that populists benefit from crisis situations. This chapter discusses the literature on crises and populism from a theoretical perspective and provides a novel framework of analysis for addressing the study of the COVID-19 crisis in the light of it...

  • Open Access English
    Authors: 
    Ludivine Grzelak; Sarah Temmam; Cyril Planchais; Caroline Demeret; Laura Tondeur; Christèle Huon; Florence Guivel-Benhassine; Isabelle Staropoli; Maxime Chazal; Jérémy Dufloo; +46 more
    Publisher: American Association for the Advancement of Science (AAAS)
    Country: France
    Project: ANR | CHIKV-Viro-Immuno (ANR-14-CE14-0015), ANR | TIMTAMDEN (ANR-14-CE14-0029), EC | RECoVER (101003589)

    It is of paramount importance to evaluate the prevalence of both asymptomatic and symptomatic cases of SARS-CoV-2 infection and their differing antibody response profiles. Here, we performed a pilot study of four serological assays to assess the amounts of anti–SARS-CoV...

  • Open Access English
    Authors: 
    Nassima Chouaki Benmansour; Julien Carvelli; Eric Vivier;
    Publisher: HAL CCSD
    Country: France
    Project: EC | TILC (694502)

    Abstract The complement system is an essential component of the innate immune system. The three complement pathways (classical, lectin, alternative) are directly or indirectly activated by the SARS‐CoV‐2 (severe acute respiratory syndrome coronavirus 2). In the most sev...

  • Open Access English
    Authors: 
    Cécile Tran Kiem; Alessio Andronico; Paolo Bosetti; Juliette Paireau; Lise Alter; Pierre-Yves Boëlle; Arnaud Fontanet; Daniel Lévy-Bruhl; Simon Cauchemez;
    Publisher: HAL CCSD
    Country: France
    Project: EC | RECoVER (101003589)

    International audience; Thrombosis with thrombocytopenia (TTS) has been identified as a rare adverse event following COVID-19 vaccination with Vaxzevria. We modelled the benefits and risks of Vaxzevria distribution from May to September 2021 in metropolitan France where...

  • Open Access English
    Authors: 
    Guillaume Castel; Mathilde Couteaudier; Frank Sauvage; Jean-Baptiste Pons; Séverine Murri; Angelina Plyusnina; Dominique Pontier; Jean-François Cosson; Alexander Plyusnin; Philippe Marianneau; +1 more
    Countries: France, Finland
    Project: EC | EDENEXT (261504), ANR | ECOFECT (ANR-11-LABX-0048), EC | ANTIGONE (278976), ANR | Avenir L.S.E. (ANR-11-IDEX-0007)

    Puumala virus (PUUV) is the agent of nephropathia epidemica (NE), a mild form of hemorrhagic fever with renal syndrome (HFRS) in Europe. NE incidence presents a high spatial variation throughout France, while the geographical distribution of the wild reservoir of PUUV, ...

  • Open Access English
    Authors: 
    Edin Hamzic; Rikke B. Kjærup; Núria Mach; Guilietta Minozzi; Francesco Strozzi; Valentina Gualdi; John L. Williams; Jun Chen; Eva Wattrang; Bart Buitenhuis; +2 more
    Publisher: HAL CCSD
    Country: France
    Project: EC | NADIR (228394)

    BackgroundAvian infectious bronchitis (IB) is an acute and highly contagious disease of the upper-respiratory tract caused by infectious bronchitis virus (IBV). Understanding the molecular mechanisms involved in the immune response to IBV infection is a crucial element ...

  • Open Access English
    Authors: 
    Marion Gransagne; Gabriel Aymé; Sébastien Brier; Gaëlle Chauveau-Le Friec; Véronique Mériaux; Mireille Nowakowski; François Dejardin; Sylvain Levallois; Guilherme D. Melo; Flora Donati; +12 more
    Publisher: HAL CCSD
    Country: France
    Project: EC | EVAg (653316)

    International audience; The current COVID-19 pandemic illustrates the importance of obtaining reliable methods for the rapid detection of SARS-CoV-2. A highly specific and sensitive diagnostic test able to differentiate the SARS-CoV-2 virus from common human coronavirus...