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The following results are related to COVID-19. Are you interested to view more results? Visit OpenAIRE - Explore.
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60 research outcomes, page 1 of 6
  • publication . Article . Other literature type . 2018
    Open Access English
    Authors:
    Sam Nooij; Sam Nooij; Dennis Schmitz; Dennis Schmitz; Harry Vennema; Annelies Kroneman; Marion P. G. Koopmans; Marion P. G. Koopmans;
    Project: EC | VIROGENESIS (634650), EC | COMPARE (643476)

    Metagenomics poses opportunities for clinical and public health virology applications by offering a way to assess complete taxonomic composition of a clinical sample in an unbiased way. However, the techniques required are complicated and analysis standards have yet to ...

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  • publication . Article . Other literature type . 2020
    Open Access English
    Authors:
    Corman, Victor M; Landt, Olfert; Kaiser, Marco; Molenkamp, Richard; Meijer, Adam; Chu, Daniel KW; Bleicker, Tobias; Brünink, Sebastian; Schneider, Julia; Schmidt, Marie Luisa; ...
    Project: EC | EVAg (653316), EC | PREPARE (602525), EC | EVA-GLOBAL (871029), EC | COMPARE (643476)

    Background The ongoing outbreak of the recently emerged novel coronavirus (2019-nCoV) poses a challenge for public health laboratories as virus isolates are unavailable while there is growing evidence that the outbreak is more widespread than initially thought, and int...

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  • publication . Article . 2018
    Open Access English
    Authors:
    Melcher, Ulrich; Rasmussen, Thomas Bruun; Boniotti, Maria Beatrice; Papetti, Alice; Grasland, Béatrice; Frossard, Jean-Pierre; Dastjerdi, Akbar; Hulst, Marcel; Hanke, Dennis; Pohlmann, Anne; ...
    Persistent Identifiers
    Project: EC | COMPARE (643476)

    Porcine epidemic diarrhoea virus, strain CV777, was initially characterized in 1978 as the causative agent of a disease first identified in the UK in 1971. This coronavirus has been widely distributed among laboratories and has been passaged both within pigs and in cell...

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  • publication . Article . 2019
    Open Access English
    Authors:
    Hjelmsø, Mathis Hjort; Mollerup, Sarah; Jensen, Randi Holm; Pietroni, Carlotta; Lukjancenko, Oksana; Schultz, Anna Charlotte; Aarestrup, Frank M.; Hansen, Anders Johannes;
    Persistent Identifiers
    Publisher: Public Library of Science
    Project: EC | COMPARE (643476)

    Human viral pathogens are a major public health threat. Reliable information that accurately describes and characterizes the global occurrence and transmission of human viruses is essential to support national and global priority setting, public health actions, and trea...

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  • publication . Article . 2020
    Open Access
    Authors:
    Eduardo Moralejo; Margarita Gomila; M. Montesinos; David Borrás; Aura Pascual; A. Nieto; Francesc Adrover; Pere A. Gost; Guillem Segui; Antonio Busquets; ...
    Publisher: Springer Science and Business Media LLC
    Project: EC | XF-ACTORS (727987)

    This work was partially funded by projects XF-ACTORS (Xylella fastidiosa Active Containment Through a Multidisciplinary-Oriented Research Strategy; grant 727987 from European Union’s Horizon 2020 Framework Research Programme) and ERTA2017-00004-02 and E-RTA2017-00004-04...

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  • publication . Article . 2014
    Open Access English
    Authors:
    Luna De Ferrari; John B. O. Mitchell;
    Publisher: BioMed Central
    Project: UKRI | Machine Learning Approach... (BB/I00596X/1)

    Background: In this work we predict enzyme function at the level of chemical mechanism, providing a finer granularity of annotation than traditional Enzyme Commission (EC) classes. Hence we can predict not only whether a putative enzyme in a newly sequenced organism has...

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  • publication . Article . 2019
    Open Access
    Authors:
    Gassen, Nils C.; Niemeyer, Daniela; Muth, Doreen; Corman, Victor M.; Martinelli, Silvia; Gassen, Alwine; Hafner, Kathrin; Papies, Jan; Mösbauer, Kirstin; Zellner, Andreas; ...
    Persistent Identifiers
    Publisher: Springer Science and Business Media LLC
    Project: EC | EVAg (653316), EC | GXE-MOLMECH (281338), EC | COMPARE (643476)

    Autophagy is an essential cellular process affecting virus infections and other diseases and Beclin1 (BECN1) is one of its key regulators. Here, we identified S-phase kinase-associated protein 2 (SKP2) as E3 ligase that executes lysine-48-linked poly-ubiquitination of B...

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  • publication . Article . Other literature type . 2018
    Open Access English
    Authors:
    Muth, Doreen; Corman, Victor Max; Roth, Hanna; Binger, Tabea; Dijkman, Ronald; Gottula, Lina Theresa; Gloza-Rausch, Florian; Balboni, Andrea; Battilani, Mara; Rihtarič, Danijela; ...
    Project: EC | COMPARE (643476)

    Abstract A 29 nucleotide deletion in open reading frame 8 (ORF8) is the most obvious genetic change in severe acute respiratory syndrome coronavirus (SARS-CoV) during its emergence in humans. In spite of intense study, it remains unclear whether the deletion actually re...

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  • publication . Article . 2019
    Open Access English
    Authors:
    Sherif A. El-Kafrawy; Victor M. Corman; Ahmed M Tolah; Saad B. Al Masaudi; Ahmed M. Hassan; Marcel A. Müller; Tobias Bleicker; Steve Harakeh; Abdulrahman A. Alzahrani; Ghaleb A. Alsaaidi; ...
    Publisher: Elsevier B.V
    Project: EC | COMPARE (643476)

    Summary: Background: The Middle East respiratory syndrome coronavirus (MERS-CoV) is a lethal zoonotic pathogen endemic to the Arabian Peninsula. Dromedary camels are a likely source of infection and the virus probably originated in Africa. We studied the genetic diversi...

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  • publication . Article . 2018
    Open Access English
    Authors:
    Wylezich, Claudia; Papa, Anna; Beer, Martin; Höper, Dirk;
    Persistent Identifiers
    Project: EC | COMPARE (643476)

    Abstract Metagenomics is currently the only generic method for pathogen detection. Starting from RNA allows the assessment of the whole sample community including RNA viruses. Here we present our modular concerted protocol for sample processing for diagnostic metagenomi...

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60 research outcomes, page 1 of 6